摘要
综述了基于青藤碱的抗风湿性关节炎分子构建的研究进展.主要包括青藤碱分子结构的化学/生物改造及其药理活性的相关研究,并探讨了其进一步深入研究的目标,为发现新的抗炎分子和先导化合物提供了参考.
In this paper, the sinomenine based molecular design of anti-RA agents were introduced, including modification of sinomenine by chemical/biologic method and bioactivity of modified compounds. Furthermore, the further research on sinomenine was also estimated in advance. This paper will give referenced instructions to find new anti- RA agents and leading compounds.
出处
《华中师范大学学报（自然科学版）》
CAS
CSCD
北大核心
2009年第1期83-91,共9页
Journal of Central China Normal University：Natural Sciences
基金
国家重点基础研究发展计划项目(2007CB714504)
