摘要
目的观察心脑舒通胶囊地冠心病心绞痛血瘀证及其对患者ET、NO水平的影响。方法60例冠心病心绞痛患者被随机分为合心爽对照组(简称对照组)和心脑舒通胶囊治疗组(简称治疗组),两组患者分别应用合心爽与心脑舒通胶囊治疗。观察两组患者的临床疗效及治疗前后ET、NO水平的变化情况。结果心脑舒通胶囊治疗冠心病心绞痛有较好的临床疗效,与对照组比较无显著性差异。两组治疗前后ET无明显变化,治疗后血浆NO均较治疗前有所升高,治疗组NO治疗后升高水平与治疗前比较有显著性差异(P<0.05)。结论心脑舒通胶囊治疗心绞痛与合心爽疗效相当,其疗效机理可能与升高血浆NO有关。
Objective To observe the impact of Xinnaoshutong Jiaonang（Capsule for promoting the circulation of the brain and heart）on blood stasis syndrome of angina pectoris and ET and NO levels.Methods 60 cases of coronary heart disease with angina pectoris were randomly divided into herbesser control group（control group）and Xinnaoshutong Jiaonang treatment group（treatment group）.Herbesser and Xinnaoshutong Jiaonang were applied in two groups respectively.It was to observe the clinical efficacy and the changes in ET and NO before and after treatment in two groups. Results Xinnaoshutong Jiaonang achieved quite good efficacy on clinical efficacy, but there was no significant difference discovered in comparison with control group. ET did not change apparently before and after treatment in two groups. After treatment, plasma NO was increased compared with that before treatment. In treatment, significant difference in the changes in NO presented in comparison before and after treatment （ P 〈 0.05 ）. Conclusion The efficacy of Xinnaoshutong Jiaonang is similar to that of herbesser on angina pectoris and its mechanism is probably related to the increase of plasma NO.
出处
《世界中西医结合杂志》
2009年第4期263-265,共3页
World Journal of Integrated Traditional and Western Medicine
关键词
心脑舒通
心绞痛
内皮素
一氧化氮
Xinnaoshutong Jiaonang
Angina pectoris
Endothelin
Nitric oxide
