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单肺通气麻醉对胸科术后病人免疫功能的影响 被引量:2

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摘要 目的:观察单肺通气麻醉对胸科病人术后免疫功能的影响。方法:51例胸外科手术的病人随机分为两组,双肺通气组(TLV组)27例,单肺通气组(OLV组)24例,分别于麻醉前1 d、手术后3、7、14 d测定血T淋巴细胞亚群、NK细胞活性和免疫球蛋白IgA、IgG、IgM浓度。结果:麻醉后TLV组CD4、CD8、NK值与麻醉前比较明显下降(P<0.05),OLT组各指标无明显变化。TLV组CD4、CD8、NK值在术后7、14 d均低于OLV组(P<0.05),其余指标组间比较无明显差异(P>0.05)。结论:单肺通气可导致机体免疫抑制,但抑制程度相对双肺通气轻。
出处 《广西医科大学学报》 CAS 北大核心 2008年第6期872-874,共3页 Journal of Guangxi Medical University
基金 广西壮族自治区科技厅课题(No.桂科自0447088)
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