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镇痛治疗对胸科病人围术期呼吸循环功能影响的临床初步探讨 被引量:3

Effects of Analgetic Treatment on Perioperative Respiration and Circulation in Patients with Intrathoracic Diseases
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摘要 作者对24例胸科手术病人(食道、贲门、肺癌、ASAⅠ~Ⅱ级,ECG异常13例,肺功能异常3例)术前预置硬膜外导管,术后病人诉疼痛时经导管注入2mg吗啡镇痛治疗,观察记录镇痛治疗前、后呼吸循环功能各项指标分别为:f(bpm)21.833±0.926,16.58310.560;VT(ml)281.667±17.053,378.333±18.993;Vc(ml)722.917±37.103,966.667±52.704;SpO2(%)97.625±0.355,98.208±0.324;HR(bpm)85.5±2.438,76.75±2.328;MAP(kPa)13.986±0.278,11.75±0.296;RPP1692.542±55.491,1214.625±49.476;前后比较各项P值均<0.01。结果表明:经镇痛治疗后呼吸循环功能明显好转或改善,且12h完全镇痛率达100%、48h镇痛率为87.5%、全组未用其它任何镇痛治疗,无呼吸抑制或严重低血压发生。因此,作者认为本法具有用药量小、镇痛效果确切可靠持久、呼吸循环功能稳定、有利胸科术后康复等特点。 xtradural catheters were placed in 24 surgical patients with intrathoracic diseases.Morphine hydrochloride 2mg was injected through the catheter if painoccurs after operations. RespiratiOn and circulation were observed be-fore and after the drug administration。 The results show that the respiration and circulation were improved signifi-cantly after analgetic treament and no respiratory depression or severe hypotension was recorded. It is concludedthat this method has the advantages of low drug dose and better pain-relieve effect, which is helpfuI to thepatients’recovery.
机构地区 江苏省肿瘤医院
出处 《临床麻醉学杂志》 CAS CSCD 北大核心 1995年第5期279-281,共3页 Journal of Clinical Anesthesiology
关键词 疼痛 吗啡 呼吸循环 胸部外科手术 硬膜外麻醉 Analgesia Morphine Respiration Circulation
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