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Glubran(NBCA-MS)胶栓塞脑动静脉畸形的临床研究 被引量:5

Endovascular embolization treatment of cerebral arteriovenous malformation with Glubran (NBCA-MS)
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摘要 目的探讨Glubran(NBCA-MS)胶栓塞脑动静脉畸形的临床技巧及治疗效果。方法在DSA监测下对96例脑动静脉畸形患者采用不同浓度的意大利GEM公司生产的Glubran(NBCA-MS)胶进行187次血管内栓塞治疗.并对患者进行跟踪随访.了解临床效果。结果96例患者中临床随访92例未再出现临床症状.症状好转3例.复发1例。48例行脑血管造影复查,其中44例畸形血管团完全消失,其余栓塞程度达80%~90%以上,进一步行γ-刀放射治疗。本组共32例栓塞后行γ-刀放射治疗,其中26例患者治疗1~2年后行DSA造影检查,21例畸形血管团完全消失。结论用Glubran(NBCA.MS)胶血管内栓塞治疗脑动静脉畸形是一种安全、有效的治疗手段。 Objective To explore the clinical skills and curative efficacy of Glubran (NBCA-MS) embolization of cerebral arteriovenous malformations. Methods Ninety-six cases of cerebral arteriovenous malformations were treated by 187 endovascular embolizations with different concentrations of Italy GEM company' s Glubran CNBCA-MS). Follow-up was performed to 96 cases of cerebral arteriovenous malformation with NBCA-MS embolization. Results During the follow-up in 96 cases, clinical symptoms completely disappeared in 92, were improved in 3 and reoccurred in 1. The malformation was totally got rid of in 44 of 48 cases DSA examinated, and the 80%-90% embolization was achieved in the rest who need further ^-knife therapy. In all cases, γ-knife therapy was performed in 32 cases after embolization, and among them 26 cases received DSA examination 1-2 years after γ-knife therapy, and 21 cases were proved to have no malformation. Conclusions The method of endovascular emdolization with NBCA-MS is safe, reliable and effective to treat the cerebral arteriovenous malformation.
出处 《中华神经医学杂志》 CAS CSCD 2008年第5期487-490,共4页 Chinese Journal of Neuromedicine
关键词 颅内动静脉畸形 栓塞 治疗性 α-氰基丙烯酸异丁酯 随访研究 Intracranial arteriovenous malformations Embolization, therapeutic NBCA Follow-up studies
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