摘要
目的探讨在 X 线监视下,经皮穿刺局部注射博莱霉素碘油乳剂(BLE)入眼眶畸形静脉内,治疗眶内静脉畸形(OVM)的疗效和安全性。方法 15例 OVM 患者,右眼6例,左眼9例,均单眼发病。病程最短2年,最长10年,平均3.9年。患者均有眼球突出,头低位或压迫颈静脉时明显。眼球突出时两侧相差≤5 mm 者11例,相差>5 mm 且≤8 mm 者4例。视力减退4例,复视2例。所有患者术前均行 CT 或 MR 检查,治疗前均先直接穿刺 OVM 造影进一步证实,明确诊断为 OVM。确诊后将 BLE 透视下缓慢注入到 OVM 内。随访8～42个月,平均随访时间为23个月。结果 15例OVM 患者均成功注入 BLE。BLE 用量为1.5～3.0 ml,平均2.2 ml。术后6～12个月所有患者眼球突出消失,眼部外观恢复正常。4例视力减退患者中的3例视力恢复,2例复视患者复视均消失。头低位或压迫颈静脉时,仍有2例轻度突出,两侧相差≤2 mm。术后患者均出现眼部肿胀,1周内消失。未见眼眶内出血、眼部瘢痕等其他并发症。结论 X 线监视下,经皮穿刺局部注射 BLE 治疗 OVM,简单易行,是一种安全有效治疗的方法。
Objective To evaluate the efficacy and safety of intralesional injection with bleomycin lipiodol emulsion （BLE） for the treatment of orbital venous malformation （ OVM ）. Methods There were 15 cases with left- sided OVM （n =9） and right- sided OVM （n =6）. All patients had proptosis. The proptosis was less than 5 mm in 11 cases, 〉 5 mm and ≤ 8 mm in d cases. The mean value was d. 2 mm. Four patients noticed reduction in their vision and two had diplopia. Those patients were examined by CT or MR. Direct venography was performed in each patient. After the diagnosis of OVM was confirmed, intralesional injection of BLE was performed. The efficacy of the treatment and complications were observed during the following 8 to 42 months （ mean 23 months）. Results The BLE were successfully injected in all the patients. All patients had resolution of proptosis and diplopia. Three patients gained improvement of visual acuity. The periorbital swelling occurred in all patients after operation and resolved within 1 week without special treatment. Other complications, such as orbital hemorrhage and periorbital scar, were not observed during following-up. Conclusion Intralesional injection with BLE is convenient, safe and efficient for the treatment of OVM.
出处
《中华放射学杂志》
CAS
CSCD
北大核心
2007年第10期1113-1115,共3页
Chinese Journal of Radiology
关键词
导管插入术
外周
眼眶
抗生素类
抗肿瘤
放射学
介入性
Catheterization, peripheral
Orbit
Antibiotics, antineoplastic
Radiology, interventional
