摘要
目的研究一种中西药联合使用对耐药菌的抑菌与杀菌效果。方法采用纸片扩散法对中西药制剂抑制耐药性鼠伤寒沙门菌的效果进行了试验观察。结果95号菌株对先锋V耐药,J9和P10号菌株对吡哌酸耐药。耐先锋V的95号菌株单用先锋V时抑菌环为8 mm,单用中药时抑制环为12 mm,中西药联合使用时抑菌环扩大到19 mm。耐吡哌酸的J9号和P10号菌株,中西药联合使用时抑菌环分别扩大到15 mm和14 mm。结论先锋V和吡哌酸分别与中药提取液联合作用可明显提高其对耐药菌的抑菌作用。
Objective To study the efficacy of a preparation of combination of Chinese and Western medicines in inhibiting and killing drug - resistant bacteria. Method Paper disc diffusion method was used to carry out experimental observation on efficacy of the preparation of combination of Chinese and Western medicines in inhibiting drug - resistant Salmonella typhimurium. Results The No. 95 strain was resistant to cephazolin, No. J9 and No. P10 strains were resistant to pipemidic acid. The inhibition zone of cephazolin - resistant No. 95 strain was 8 mm when only cephazolin was used and was 12 mm when only the Chinese medicine was used, while the inhibition zone increased to 19 mm when the Chinese and Western medicines were used in combination. The inhibition zones of pipemidic acid - resistant No. J9 and No. P10 strains increased to 15 mm and 14 mm respectively when the Chinese and Western medicines were used in combination. Condusions Cephazolin and pipemidic acid in combination with Chinese medicine extract respectively can significantly enhance their bacteriostatic effects on the drug-resistant bacteria.
出处
《中国消毒学杂志》
CAS
北大核心
2008年第2期156-158,共3页
Chinese Journal of Disinfection
关键词
中西药结合
耐药菌
抑菌效果
药敏试验
combination of Chinese and Western medicines
drug - resistant bacteria
bacteriostatic efficacy
drug sensitivity test
