摘要
目的了解鲍氏不动杆菌在四川北部地区的临床分布特点及耐药情况。方法按常规方法分离培养临床住院患者送检的各种样本;采用法国生物梅里埃(API)公司生产的VITEK-32全自动微生物鉴定及药敏系统对收集的样本进行菌株鉴定和药敏试验;按NCCLS标准判定检验结果。结果在分离得到的78株鲍氏不动杆菌中,来自痰标本和重症监护病房(ICU)标本中鲍氏不动杆菌的比率较高,而且这些分离株除了对亚胺培南和美罗培南较为敏感外,对其他19种所试抗菌药物的耐药率均较高。结论在四川北部地区,鲍氏不动杆菌是引起危重病人呼吸道感染的较常见致病菌,对现有多种抗菌药物耐药严重,提示临床医生必须对该菌所致感染予以高度重视,同时应加强其治疗用药选择的合理性。
Objective To investigate the distribution and drug resistance ofAcinetobacter Baumanii clinical isolates in North Sichuan Area. Methods 78 strains ofAcinetobacter Baumanii were isolated from various kinds of specimens collected from hospitalized patients, and identified by VITEK-32 System of Drug-susceptibility. The results were assessed with NCCLS. Results Acinetobacter Baumanii was especially common in sputum and the specimens from intensive care unit （ICU）. 78 isolates ofAcinctobactcr Baumanii were high resistant to 19 tested antibiotics except for Imipenem （IMP） and Meropenem （MEP）. Conclusion Acinetobacter Baumanii is a common cause of respiratory tract infection in North Sichuan Area, and shows very high resistance rate to the currently clinically used antibacterial agents. Therefore, it is important that clinicians pay great attention to the infections caused by Acinetobacter Baumanii and enhance the rationality of drug use in their treatment.
出处
《国外医药（抗生素分册）》
CAS
2008年第2期68-70,共3页
World Notes on Antibiotics
基金
四川省教育厅重点科研项目(2004A071)资助
关键词
鲍氏不动杆菌
医院感染
临床分布
耐药性
Acinctobactcr Baumanii
Hospital infection
Clinical distribution
Drug-resistance
