期刊文献+

丙三醇缩水甘油醚改性脱细胞猪真皮基质的研究 被引量:4

Study on procine acellular dermal matrix modified by glycerol polyglycidyl ether
下载PDF
导出
摘要 研究了丙三醇缩水甘油醚(GPE)改性脱细胞猪真皮基质材料(pADM)的基本性能.通过考察不同温度、pH值、用量和反应时间对改性材料(GPE-pADM)性能的影响,初步探讨了改性条件与改性材料性能之间的关系.实验结果表明:反应温度37~42℃,pH值10.0~10.5,反应时间48-72h,用量8%时综合性能较好.交联后材料的接触角明显降低,且随着GPE用量的增加,接触角降低程度增大,表明交联提高了材料的亲水性能. The basic performance of Procine acellular dermal matrix (pADM) were studied after modified by glycerol polyglycidyl ether. The relation between the modified material and properties of modified material was discussed preliminarily, through researching on performance of the GPE-pADM influenced by the different temperature, pH, dosage and reaction time. It is showed that the comprehensive performance was best when the reaction temperature was 37-42℃, the pH was 10.0-0.5, the reaction time was 48-72h and dosage was 8%. The contact angle of the crosslinked material was reduced obviously, and the more dosage of GPE was used, the more reduced extent of contact angle was. It is indicated that the hydrophilic performance of the material had been improved by cross-linking.
出处 《功能材料》 EI CAS CSCD 北大核心 2007年第A09期3523-3526,共4页 Journal of Functional Materials
基金 成都市科技攻关计划资助项目(06GGYB965GX-030)
关键词 丙三醇缩水甘油醚 改性 脱细胞猪真皮基质 胶原 glycerol polyglycidyl ether modification procine acellular dermal matrix collagen
  • 相关文献

参考文献7

二级参考文献32

  • 1余喜讯,成敏,陈槐卿.改造天然生物组织为血管支架材料的预处理方法[J].生物医学工程学杂志,2004,21(3):476-481. 被引量:23
  • 2黄靖雄.环氧乙烷灭菌[J].中华医院感染学杂志,2004,14(12):1435-1439. 被引量:67
  • 3刘侠,乐以伦,黄嘉,石应康,程述森,安琪.环氧改性与戊二醛处理的牦牛心包的扫描电镜形态比较[J].生物医学工程学杂志,1996,13(3):200-203. 被引量:4
  • 4邢其毅 徐瑞秋 等.基础有机化学[M].北京:高等教育出版社,2000.354-368. 被引量:5
  • 5Sung H W,Shen S H,Tu R,et al.Comparison of the crosslinking characteristics of the porcine heart valves fixed with glutaraldehyde or epoxy compound.ASAIOJ,1993,39:532 被引量:1
  • 6Hsing Wen Sung,Chein Sheng Hsu,Yuag Shein Lee,et al.Crosslinking characteristics of an epoxy-fixed porcine tendon:Effects of pH,temperature,and fixative concentration.J Biomed Mater Res,1996,31:511 被引量:1
  • 7Tu R,Shen S H,Lin D,et al.Fixation of bioprosthetic tissues with monofunctional and multifunctional polyepoxy compounds.J Biomed Mater Res,1994,28:677 被引量:1
  • 8Zeeman R,Dijkstra P J,Wachem P Bvan,et al.Cross linking and modification of dermal sheep collagen using 1,4-butanediol diglycidyl ether.J Biomed Mater Res,1999,46(3):424 被引量:1
  • 9Ivan S,Alferiev,John T Hinson,Matthew Ogle,et al.High reactivity of alkyl sulfides towards epoxides under conditions of collagen fixation a convenient approach to 2-a-mino-4 butyrolactones.Biomaterials,2001,22:2501 被引量:1
  • 10Lee J M,Pereira C A,Kan L W K.Effect of molecular structure of poly (glycidyl ether) reagents on cross-linking and mechanical properties of bovine pericardial xenograft materials.J Biomed Mater Res,1994,28:981 被引量:1

共引文献36

同被引文献23

引证文献4

二级引证文献17

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部