摘要
目的研究灵芝提取物的镇痛与抗炎作用。方法用冰醋酸化学刺激疼痛模型和二甲苯诱导的鼠耳肿胀炎症模型,观察灵芝提取物的镇痛作用与抗炎作用。结果灵芝提取物能明显减少冰醋酸诱导的小鼠扭体次数(P<0.01),对二甲苯诱导的鼠耳肿胀有明显的抑制作用(P<0.01)。结论灵芝提取物具有镇痛和抗炎作用。
Objective：To explore the anti-inflammatory and analgesic effects of Ganoderma lucidum extractive. Methods：Analgeslc and anti-inflammatory effects were detected by analgesic model of mice twist and inflammatory model of dimethyl-benzene-induced ear swelling in mice. Results：Ganoderma lucidum extractive decreased the rolling reaction times of mice, and restrained the swelling of mice ears at the doses of 0. 015g/kg and 0, 030g/kg（P〈0.01 ） Conclusion： Ganoderma lucidum extractive has analgesic and anti-inflammatory effects.
出处
《泰山医学院学报》
CAS
2006年第2期102-103,共2页
Journal of Taishan Medical College
关键词
灵芝
镇痛
抗炎
小鼠
Ganoderma lucidum
analgesic
anti-inflammatory
mice
