摘要
目的:研究用姜黄生产姜黄素的实用生产工艺。方法:渗漉法提取及大孔树脂分离正交试验。结果:提取姜黄素用9倍体积的70%乙醇,以3 mL/min的速度渗漉为最佳提取工艺;利用D101大孔树脂纯化姜黄素工序中调节上样料液pH为7,用80%乙醇以4 mL/min的速率洗脱为最佳分离工艺。结论:渗漉法提取和大孔树脂分离获得姜黄素的工艺简便、实用、经济,适用于小量生产。
Objective： To establish the optimal technology for extraction and isolation of eureumin from Curcuma longa L.. Methods： Orthogonal design was applied to percolation and isolation with macroporous resin, Results： The optimal extraction method was that Curcuma longa L. decoction was percolated with 9-fold volume of 70% ethanol at the velocity of 3 mL/min and the optimal isolation technology was that the pH of curcumin sample solution was regulated to 7 by 0. 01 mol/L HCI and 0. 01 mol/L NaOH solution and 80% ethanol was used for elution of the velocity of 4 mL/min. Conclusion： This technology of extraction with percolation and isolation with D101 macroporous resin is simple, economic and could be applied to producing small amount of curcumin.
出处
《药学服务与研究》
CAS
CSCD
2006年第4期277-279,共3页
Pharmaceutical Care and Research
关键词
姜黄属
姜黄素
分离和提纯
工艺学
curcuma
curcumin
isolation and purification
technology
