摘要
肿瘤的侵袭和转移是多基因多因子共同作用的结果。据推测nm23-H1基因可能仅为转移相关基因的上游调节基因,它对肿瘤转移潜能的抑制作用是通过下游基因实现的。本文重点对nm23-H1的分子生物学、nm23-H1的相关因素及其与肿瘤侵袭转移的组织病理相关性研究进展进行综述。
The invasion and metastasis of neoplasm in the interactive effect by diverse gene and factors. Nm23 -H1 maybe a upstream controlling gene to metastasis related gene, and implement it＇s depressant effect to metastasis potency of tumor by downstream gene. We review the research development about nm23 - H1, including some interactive factors and the dependability between invasion and metastasis of neoplasm and histopathology.
出处
《现代肿瘤医学》
CAS
2006年第9期1166-1168,共3页
Journal of Modern Oncology
