摘要
目的:观察2型糖尿病患者下肢动脉血管病变的彩色多普勒血流显像特点。方法:选择2003-01/2005-03在哈尔滨医科大学附属第二医院内分泌科住院的2型糖尿病患者40例作为病例组,另选正常体检者30例作为正常对照组,均自愿参加观察。分别进行彩色多普勒血流显像检查,观察两组下肢动脉血管走行,管腔有无狭窄,是否有硬化斑块形成。测量下肢动脉内膜-中层厚度,观察频谱特征,测量收缩期峰值流速、搏动指数和阻力指数。结果:病例组40例和对照组30例全部进入结果分析,无脱落。①两组观察对象的彩色及频谱多普勒血流显像结果比较:正常对照组血管走行平直,血流充盈良好、血流颜色正常;血流呈三相波,频带较窄,收缩期下面有一个无血流信号的窗。病例组血管走行弯曲,硬化斑块形成,管腔狭窄,狭窄处血流充盈缺损,呈稀疏血流或花彩血流;血流呈两相波或单相波,重者出现湍流连续频谱,频带较宽,频窗消失。②两组观察对象的血管内径、内膜-中层厚度及血流动力学参数比较:胫后动脉、足背动脉内径较正常对照组变细,血流速度减慢(P<0.05);内膜-中层厚度较正常对照组增厚,搏动指数、阻力指数较正常对照组增大(P<0.05)。结论:彩色多普勒血流显像可以明确地反映动脉的病变情况,较准确地测量血流动力学参数,可为临床动态评估糖尿病患者下肢动脉粥样硬化的发生发展及其防治提供客观依据。
AIM： To observe the characteristics of color Doppler flow imaging （CDFI） of artery pathology of lower limbs in type 11 diabetics.
METHODS： Forty inpatients with type 11 diabetes mellitus （case group） were selected from the Department of Endocrinology, the Second Affiliated Hospital of Harbin Medical University between lanuary 2003 and March 2005, and another 30 normal physical examinees were taken as normal controls （normal control group）. CDFI was performed in all the subjects. The tortousity of lower limbs artery and whether there were stenosis and plaques were observed. The intima-media thickness （IMT）, systolic peak velocity, pulsitive index, resistance index （RI） were measured respectively.
RESULTS： All the 40 patients and 30 normal subjects entered the analysis of results. （1） Comparison of the results of CDFI and spectral Doppler flow imaging between the two groups： In the control group, the vascular courser was parallel, flow filling was good, flow color was normal, the flow showed triphasic wave, band was narrower, and there was a window below without blood flow signal. In the case group, the vessels were narrow and tortuous, and there were some plaques in them. On color imaging, the blood flow was turbulence, sparse or bright at the site of stenosis. The spectrum showed the two waves or single wave on Doppler spectrum. In severe stenosis, the spectrum was continuous companying with wide frequency band and disappeared spectral window. （2） The diameters of arteria tibialis posterior and arteria dorsalis pedis were thinner and the velocity was slower in the case group than those in the control group （P 〈 0.05）. The IMT was thicker and pulsitive index and resistance index were increased in the case group, and there were significant difference （P 〈 0.05）.
CONCLUSION： CDFI can reflect artery pathology and measure hemodymamic parameters accurately, and provide clinic diagnostic methods for dynamic observing on occurrence and development of diabetes athero
出处
《中国临床康复》
CAS
CSCD
北大核心
2005年第43期134-135,i0002,共3页
Chinese Journal of Clinical Rehabilitation
