摘要
目的:探讨低能量氦氖激光血管内照射(intravascularlaserirradiationofblood,ILIB对急性脑卒中患者血液流变学变化及血脂水平的影响,并)设对照组比较其作用差异。方法:1999-01/2004-05,解放军第三军医大学西南医院康复中心收治的82例急性脑梗死患者,将患者分治疗组和对照组各41例,对照组口服阿司匹林肠溶片300mg,1次/d,治疗组加用低能量氦氖激光血管内照射,观察两组治疗30d前后疗效及比较血液流变学和血脂指标的变化。结果:治疗组疗效明显优于对照组,两组治愈显效率分别为37%和27%,总有效率为93%和81%(χ2=4.34,P<0.05)。血液流变学指标:全血黏度、高切值(200s-1)、中切值(30s)、低切值(3s)及血-1-1浆黏度、血细胞比容、纤维蛋白原、全血还原黏度、红细胞聚集指数、红细胞刚性指数、红细胞变形指数、红细胞电泳时间、红细胞计数、卡松黏度、卡松屈服应力和血脂中总胆固醇、三酰甘油、载脂蛋白B,治疗前后对比及与对照组比较,差异均有显著性意义(P<0.01或0.05)。结论:低能量氦氖激光血管内照射能改善急性梗死患者血液流变学指标及降低部分血脂水平。
AIM: To investigate the effects of low energy He Ne intravascular laser irrad iation of blood(ILIB) on the changes of hemorheology and the level of blood lipi d for acute stroke patients, and compare the difference with control group. METHODS: A total of 82 patients with acute cerebral infarction, selected from the Center of Rehabilitation, Third Military Medical University of Chinese PLA f rom January 1999 to May 2004, were randomly divided into treatment group and con trol group with 41 patients in each group. The patients in control group were gi ven 300 mg aspirin enteric coated tablet once a day, and patients in treatment group were given low energy He Ne ILIB. Before and after 30 day treatment, the changes of hemorheology and blood lipid were observed and compared respectively in these two groups. RESULTS: In these two groups, the cure rates were 37%and 27%respectively, an d the general effective rates were 93%and 81%(χ2=4.34, P< 0.05). The results show that the effect of treatment group was greater than that of control group. The index of hemorheology was total blood viscosity, high shearing viscosity (2 00 s-1), moderate shearing viscosity(30 s-1), low shearing viscosity (3 s-1 ), plasma viscosity, red cell haematocrit, fibrinogen, whole reduced blood visco sity, index of RBC aggregation, rigid index of RBC, deformation index of RBC, RB C electrophoresis time, RBC count, Casson viscosity, Casson yield stress, total cholesterol of blood lipid, triacylglycerol and apolipoprotein B, which were sig nificant difference compared with those of control group before and after treatm ent (P< 0.01 or 0.05). CONCLUSION: The low energy He Ne ILIB can improve the index of hemorheology a nd decrease the level of part blood lipid in acute cerebral infarction patients.
出处
《中国临床康复》
CSCD
北大核心
2005年第1期66-67,69,共3页
Chinese Journal of Clinical Rehabilitation
