摘要
为探讨直肠黏膜渗液FH检测用于评估直肠癌非手术治疗效果的价值,选择2017年2月至2020年2月于我院就诊且接受非手术治疗的120例直肠癌患者为研究对象,分别于治疗前、中、后3个阶段对患者进行肠镜检查及直肠黏膜渗液FH检测,比较2种方式的检查结果,并分析它们的一致性。结果显示,治疗前肠镜检查及直肠黏膜渗液FH检测阳性率分别为100%(120/120)和96.67%(116/120),治疗中分别为60.83%(73/120)和56.67%(68/120),治疗后分别为30.00%(36/120)和25.00%(30/120)。3个阶段肠镜检查及直肠黏膜渗液FH检测结果比较差异均无统计学意义,P>0.05。治疗中、治疗后肠镜检查和直肠黏膜渗液FH检测结果的相关性分析显示,Kappa系数分别为0.789和0.872,说明两种方法检测结果具有高度一致性或几乎完全一致。结果表明,直肠黏膜渗液FH检测用于评估直肠癌非手术治疗效果,与肠镜检查结果具有较高一致性,可将其作为评估直肠癌非手术治疗效果的重要参考指标。
This study was to explore the value of detecting rectal mucosa exudation free ferroprotoporphyrin(FH)to evaluate the efficacy of no-surgical treatment of rectal cancer,enrolled 120 cases met above conditions and received this treatment as research objectives:they received enteroscopy and FH detection at following stages as before treatment,intra-treatment,and post-treatment;then the results of above inspections were compared each to other,and the accordance was found out.As results,before treatment:the positivity ratio was respectively 100%(120/120)and 96.67%(116/120)and 25.00(30/120).Between the three stages’results of both inspections there was no statistical difference(P>0.05).Relativity analysis showedκcoefficient was respectively 0.789 and 0.872 which mark both’s high accordance,or almost accordance.Results show that detecting free ferroproto porphyrin(rectal mucosa exudation FH)to evaluate the efficacy of no-surgical treatment of rectal cancer has high accordance results with enteroscopy’s one,which it could be taken as important reference norm to evaluate the efficacy of no-surgical treatment of rectal cancer.
作者
刘苏莹
LIU Su-ying(Dept.of Clinical Laboratory,Luohe City's Central Hopsital,Luohe,Henan 462000)
出处
《中国肛肠病杂志》
2021年第11期16-17,共2页
Chinese Journal of Coloproctology
关键词
细胞游离亚铁原卟啉
肠镜检查
直肠癌
疗效判定
一致性
Free ferroprotoporphyrin(FH)
Enteroscopy
Rectal cancer
Effect determination
Accordance
