摘要
目的探讨手术联合化疗治疗耐多药肺结核的临床疗效。方法选择2012年2月至2017年2月期间新疆维吾尔自治区胸科医院收治的25例耐多药肺结核患者作为研究对象,均采取手术联合化疗方案治疗,观察患者的痰菌转阴率、并发症发生率及复发率。结果患者6个月、12个月、24个月时的痰菌转阴率分别为20(80.0%)、21(84.0%)、22(88.0%),提示手术联合化疗能显著改善患者的痰菌转阴率,促进疾病转归;统计分析发现,耐药种类越多,患者的痰菌转阴率越低,并发症越高,复发率越高。结论采用手术联合化疗治疗耐多药肺结核的临床效果显著,患者的痰菌转阴率更高,术后并发症发生率及复发率更低,该法值得在临床上推广。
Objective To explore the clinical effect of operation combined with chemotherapy in the treatment of MDR-TB.Methods From February 2012 to February 2017,25 cases of MDR-TB patients admitted to Chest Hospital of Xinjiang Uygur Autonomous Region were selected as the study objects,all of them were treated with surgery combined with chemotherapy,and the sputum bacteria conversion rate,complication rate and recurrence rate were observed.Results The negative rate of sputum bacteria was 20(80.0%),21(84.0%)and 22(88.0%)at 6 months,12 months and 24 months,respectively,suggesting that surgery combined with chemotherapy can significantly improve the negative rate of sputum bacteria and promote the outcome of the disease;statistical analysis found that the more drug-resistant types,the lower the negative rate of sputum bacteria,the higher the complications and the higher the recurrence rate.Conclusion Clinical effect of operation combined with chemotherapy in the treatment of MDR-TB is significant,the sputum bacteria conversion rate of patients is higher,the incidence of postoperative complications and recurrence rate is lower,and this method is worth popularizing in clinical practice.
作者
鱼宁
陈志祥
车勇
肖开提·米吉提
YU Ning;CHEN Zhixiang;CHE Yong;XIAO kaiti·mijiti(Chest Hospital of Xinjiang Uygur Autonomous Region,Urumqi,Xinjiang 830049,China)
出处
《新疆医学》
2020年第5期426-428,共3页
Xinjiang Medical Journal
基金
国家科技重大专项(项目编号:2018ZX10302302)
