摘要
目的了解涂阳肺结核病人的临床特点,为肺结核的防治任务提供依据。方法对2013年10月-2016年10月在新疆维吾尔自治区中医医院收治的72例涂阳肺结核患者的病例进行回顾性分析。结果(1)临床表现中咳嗽咳痰占93.1%,乏力占50%(2)体温方面,体温正常占30.6%、低热占33.3%,中等度热占16.7%,高热占19.4%。(3)肺CT:病变累及1个、2个肺野、3个及3个以上分别占20.8%、23.6%、55.6%;胸膜增厚占54.2%,渗出实变占50%,空洞占45.9%。(4)72例涂阳患者行PPD检测,PPD反应强度在阴性、弱阳性、阳性及强阳性分别占26.4%、16.7%、51.4%及5.5%;其中46例行结核感染T细胞斑点试验(tuberculosis T cell spot detection,T-SPOT.TB)检测,其阳性占67.4%。(5)15~35岁、35~55岁和>55岁患者T-SPOT.TB敏感性分别为100%、100%和42.3%;病程时间在<0.5月、0.5~1月、>1月患者T-SPOT.TB敏感性分别为100%、90.1%和45.5%;结论血清T-SPOT.TB的敏感性高于PPD的敏感性,高龄及病程长是影响T-SPOT.
Objective To understand the clinical characteristics of smear-positive pulmonary tuberculosis patients, to provide evidence for the prevention and treatment of tuberculosis. Methods A retrospective analysis was made on 72 cases of smear-positive pulmonary tuberculosis patients admitted to the Traditional Chinese Medicine Hospital ofXinjiang Uygur Autonomous Region from October2013 to October 2016. Results（1）In the clinical manifestations of cough and expectoration were accounted for 93.1%, accounted for50% of fatigue（2） temperature, normal temperature, low heat were accounted for 30.6% accounted for 33.3%, moderate fever was accounted for 16.7%, accounted for 19.4%.（3） lung CT： lesions involving 1, 2 lung fields, 3 and more than 3 accounted for 20.8%, 23.6%,55.6%; pleural thickening accounted for 54.2%, exudation accounted for 50%, cavity accounted for 45.9%.（4） 72 cases of smear positive patients were detected by PPD, and the PPD reaction intensity was negative, weak positive, positive and strong positive, accounting for26.4%, 16.7%, 51.4% and 5.5%, respectively; including 46 cases of tuberculosis infection of T cells（tuberculosis T spot test cell spot detection, T-SPOT.TB） detection, the positive rate was 67.4%.（5） 15-35 years, 35-55 years old and older than 55 years with the sensitivity of T-SPOT.TB were 100%, 100% and 42.3%; the duration in 0.5 months, 0.5-1 months, 1 months with the sensitivity of T-SPOT.TB were 100%, 90.1% and 45.5%. Conclusion The sensitivity of T-SPOT.TB was higher than that of PPD the sensitivity of old age, and disease duration are independent risk factors of T-SPOT.TB.
出处
《新疆医学》
2018年第1期47-50,共4页
Xinjiang Medical Journal
关键词
涂阳肺结核
结核感染T细胞斑点试验
临床特点
Smear Positive Pulmonary Tuberculosis
Tuberculosis T Cell Spot Detection
Clinical Features
