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氨氯地平阿托伐他汀钙片治疗高血压、冠心病合并颈动脉粥样硬化患者的疗效观察 被引量:1

Curative Effect Observation of Amlodipine and Atorvastatin in Treatment of Hypertension,Coronary Heart Disease and Carotid Atherosclerosis
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摘要 目的观察对比高血压、冠心病合并颈动脉粥样硬化治疗中氨氯地平阿托伐他汀钙片的治疗效果及影响。方法选取2016年5月至2019年3月期间本院收治高血压、冠心病合并颈动脉粥样硬化患者共74例设为研究对象,开展回顾性研究分析。根据患者治疗方案的选择将其分为对照组与观察组,各37例。对照组接受常规治疗+氨氯地平方案,观察组接受常规治疗+氨氯地平阿托伐他汀钙片方案。对比治疗前后两组血压、血脂及颈动脉内膜中层厚度变化。结果两组血压、血脂及颈动脉内膜中层厚度入院指标组间对比无明显差异(P>0.05)。经治疗后,相较对照组,观察组血压、血脂指标及颈动脉内膜中层厚度均有明显下降(P<0.05)。结论高血压、冠心病合并颈动脉粥样硬化临床治疗中氨氯地平阿托伐他汀钙片的应用,可在改善患者血流动力学指标同时,改善血脂异常,减少颈动脉内膜中层厚度,降低疾病风险。 Objective to observe and compare therapeutic effect of amlodipine atorvastatin calcium tablets in treatment of hypertension and coronary heart disease combined with carotid atherosclerosis.Methods choose 74 cases hypertension and coronary heart disease patients combined with carotid atherosclerosis in our hospital from May 2016 to March 2019 as research objects,and carry on review and analysis.Divide them into control group and observation group according to choice of treatment scheme,37 cases in each.Control group received routine treatment+amlodipine regimen,and observation group received routine treatment+amlodipine atorvastatin calcium tablet regimen.Compare changes in blood pressure,lipids,and carotid intima-media thickness between two groups before and after treatment.Results there were no significant differences in blood pressure,blood lipids,and carotid intima-media thickness between two groups(P>0.05).After treatment,blood pressure,lipid index,and carotid intima-media thickness in observation group decreased more significantly than control group(P<0.05).Conclusion amlodipine atorvastatin calcium tablets can improve hemodynamic parameters,dyslipidemia,reduce carotid intima-media thickness and reduce disease risks in clinical treatment of hypertension and coronary heart disease combined with carotid atherosclerosis.
作者 马清华 MA Qing-hua(Heze City Hospital of Traditional Chinese Medicine,Heze,Shandong 274000)
机构地区 菏泽市中医医院
出处 《智慧健康》 2020年第9期186-187,共2页 Smart Healthcare
关键词 氨氯地平阿托伐他汀钙片 高血压 冠心病 颈动脉粥样硬化 治疗效果 Amlodipine atorvastatin calcium tablets Hypertension Coronary heart disease Carotid atherosclerosis Curative effect
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