目的探讨大株红景天注射液联合硫辛酸对缺血性脑卒中患者氧化应激的影响。方法选择医院收治的缺血性脑卒中患者80例,随机分为对照组和治疗组,各40例。两组患者均给予常规治疗,对照组患者加用依达拉奉30 mg静脉滴注,2次/日;治疗组患者加...目的探讨大株红景天注射液联合硫辛酸对缺血性脑卒中患者氧化应激的影响。方法选择医院收治的缺血性脑卒中患者80例,随机分为对照组和治疗组,各40例。两组患者均给予常规治疗,对照组患者加用依达拉奉30 mg静脉滴注,2次/日;治疗组患者加用大株红景天注射液10 m L联合硫辛酸注射液12 m L,静脉滴注1次/日。两组均以7 d为1个疗程,治疗3个疗程。结果治疗后,两组美国国立卫生研究院卒中量表(NIHSS)评分及血清中氧化型低密度脂蛋白(ox-LDL)、丙二醛(MDA)水平均显著降低(P<0.01),且治疗组下降幅度更明显(P<0.01);超氧化物歧化酶(SOD)、过氧化氢酶(CAT)及谷胱甘肽过氧化物酶(GSH-Px)水平均明显增高(P<0.01),且治疗组增高幅度更明显(P<0.01);治疗组总有效效为92.50%,明显高于对照组的85.00%(P<0.01);两组均未见明显不良反应。结论大株红景天注射液联合硫辛酸能有效减轻急性缺血性脑卒中患者脑内氧化应激损伤,疗效显著,不良反应少,其机制可能与抑制ox-LDL及MDA表达,上调SOD,GSH-Px和CAT水平相关。展开更多
Large engineering plants （LEPs） have certain unique features that necessitate a maintenance strategy that is a combination of both time and condition based maintenance. Although this requirement is appreciated to va...Large engineering plants （LEPs） have certain unique features that necessitate a maintenance strategy that is a combination of both time and condition based maintenance. Although this requirement is appreciated to varying degrees by asset owners, applied research leading to a systematic development of such a maintenance strategy is the need of the day. Such a strategy should also adopt a wholesome ＂systemic＂ approach so that the realization of the overall objectives of maintenance is maximized. E-maintenance has several potential benefits for large engineering plants. In this paper, a three pronged strategy is suggested for the successful implementation of e-maintenance for LEPs. Firstly, an integrated condition and time based maintenance framework is proposed for LEPs. Secondly, reference is drawn to models for condition and time based maintenance at systemic levels. As a part of the ab initio development of a condition monitoring system for a LEP, one of the characteristics of the condition monitoring system, namely, predictability, is discussed in detail as a sample for a systemic study. Thirdly, emphasis is laid on the information and expertise available in the domain of plant design, operation and maintenance and the same is tapped for incorporation in maintenance decision making.展开更多
文摘目的探讨大株红景天注射液联合硫辛酸对缺血性脑卒中患者氧化应激的影响。方法选择医院收治的缺血性脑卒中患者80例,随机分为对照组和治疗组,各40例。两组患者均给予常规治疗,对照组患者加用依达拉奉30 mg静脉滴注,2次/日;治疗组患者加用大株红景天注射液10 m L联合硫辛酸注射液12 m L,静脉滴注1次/日。两组均以7 d为1个疗程,治疗3个疗程。结果治疗后,两组美国国立卫生研究院卒中量表(NIHSS)评分及血清中氧化型低密度脂蛋白(ox-LDL)、丙二醛(MDA)水平均显著降低(P<0.01),且治疗组下降幅度更明显(P<0.01);超氧化物歧化酶(SOD)、过氧化氢酶(CAT)及谷胱甘肽过氧化物酶(GSH-Px)水平均明显增高(P<0.01),且治疗组增高幅度更明显(P<0.01);治疗组总有效效为92.50%,明显高于对照组的85.00%(P<0.01);两组均未见明显不良反应。结论大株红景天注射液联合硫辛酸能有效减轻急性缺血性脑卒中患者脑内氧化应激损伤,疗效显著,不良反应少,其机制可能与抑制ox-LDL及MDA表达,上调SOD,GSH-Px和CAT水平相关。
文摘Large engineering plants （LEPs） have certain unique features that necessitate a maintenance strategy that is a combination of both time and condition based maintenance. Although this requirement is appreciated to varying degrees by asset owners, applied research leading to a systematic development of such a maintenance strategy is the need of the day. Such a strategy should also adopt a wholesome ＂systemic＂ approach so that the realization of the overall objectives of maintenance is maximized. E-maintenance has several potential benefits for large engineering plants. In this paper, a three pronged strategy is suggested for the successful implementation of e-maintenance for LEPs. Firstly, an integrated condition and time based maintenance framework is proposed for LEPs. Secondly, reference is drawn to models for condition and time based maintenance at systemic levels. As a part of the ab initio development of a condition monitoring system for a LEP, one of the characteristics of the condition monitoring system, namely, predictability, is discussed in detail as a sample for a systemic study. Thirdly, emphasis is laid on the information and expertise available in the domain of plant design, operation and maintenance and the same is tapped for incorporation in maintenance decision making.
