Surface-enhanced Raman scattering （SERS） has emerged as an excellent analytical tool for the effective detection and fingerprint identification of various chemicals. Recently, significant progress has been made in t...Surface-enhanced Raman scattering （SERS） has emerged as an excellent analytical tool for the effective detection and fingerprint identification of various chemicals. Recently, significant progress has been made in the fabrication of SERS-active substrates using simple, inexpensive, and affordable methods. The full potential of universal SERS diagnostics will likely be realized with the development of approaches and devices capable of effectively detecting analytes on various surfaces as well as in multicomponent media. In addition, the combination of implantable or wearable SERS-active substrates and remote portable devices enables real-time diagnostics that ideally fit the concept of personalized medicine. In this paper, we summarize recent achievements in fabricating flexible SERS substrates made of cellulose paper, polymer membranes, and textile fibrous films. Emphasis is placed on the in-situ extraction and detection of various chemicals in real-world surfaces and complex media using flexible nanofibrous SERS platforms. The potential SERS applications and future perspectives in on-site diagnostics are also discussed.展开更多
An electrospun poly（lactide-co-glycolide） （PLGA） membrane was prepared and used to perform the anti-adhesion of Achilles tendon. Throughout the experiments, the membrane showed an appropriate degradation rate, and...An electrospun poly（lactide-co-glycolide） （PLGA） membrane was prepared and used to perform the anti-adhesion of Achilles tendon. Throughout the experiments, the membrane showed an appropriate degradation rate, and the pH values of degradation media were maintained at around 7.4. Simultaneously, the excellent biocompatibility of the membrane in vitro and in vivo was confirmed by live/dead and histopathological analyses. Meanwhile, the membrane can reduce tendon adhesion significantly and promote functional recovery effectively. The encouraging results were further demonstrated by hematoxylin and eosin （H＆E）, and Masson＇s trichrome stainings, and type I collagen immunohistochemical analysis. It was concluded that the model treated with the electrospun PLGA membrane was significantly better with respect to the adhesion prevention and tissue repair than that without treatment. Considering the results of degradation and adhesion prevention efficacy, the electrospun PLGA membrane would be a great candidate for the prevention of postoperative tendon adhesion.展开更多
In order to encapsulate and controlled-release bioactive proteins,three fibrous membranes,i.e.,poly（L-lactide-co-glycolide）（PLGA）,hybrid PLGA and chitosan（H-PLGA/CS）,and core/shell PLGA/CS （C-PLGA/CS）,were pro...In order to encapsulate and controlled-release bioactive proteins,three fibrous membranes,i.e.,poly（L-lactide-co-glycolide）（PLGA）,hybrid PLGA and chitosan（H-PLGA/CS）,and core/shell PLGA/CS （C-PLGA/CS）,were produced by emulsion electrospinning,co-electrospinning and coaxial electrospinning,respectively.Bovine serum albumin（BSA） was selected as a model protein.The loading efficiency of BSA in the PLGA membrane was 1.56%,lower than those of H-PLGA/CS（5.98%） and C-PLGA/CS（4.80%）.BSA release profiles from the three membranes showed initial burst releases in the first 7 d and then sustained release for 28 d.Cumulative releases at the end of the releasing period,28 d,from the above three membranes were nearly 63%,88% and 94%,respectively,indicating that the introduction of chitosan and the core/shell fiber structure could enhance BSA release rate.In addition,all these electrospun membranes could retain their fibrous morphologies after in vitro release of BSA for 28 d.展开更多
静电纺丝纳米纤维膜作为锂离子电池隔膜使用时具有优良的性能,但是由于纤维间抱合力较小,强度较低,其应用受到了极大限制。通过耐高温相PAN与低熔点相PVDF两种聚合物混纺,并经过适当的热压后处理,使PVDF部分熔融形成点粘结,制备PAN-PVD...静电纺丝纳米纤维膜作为锂离子电池隔膜使用时具有优良的性能,但是由于纤维间抱合力较小,强度较低,其应用受到了极大限制。通过耐高温相PAN与低熔点相PVDF两种聚合物混纺,并经过适当的热压后处理,使PVDF部分熔融形成点粘结,制备PAN-PVDF复合纳米纤维膜,并测试其相关性能。发现在保留静电纺膜优良性能的前提下,其强度相对处理前提高了近10倍,并表现出良好的电化学性能:室温下离子电导率达到1.32×10-3S/cm,聚合物电解质分解电压高达5.24 V,界面阻抗仅为45Ω,0.2 C首次放电比容量高达152 m Ah/g,综合性能远优于美国CELGARD2400。展开更多
A kind of octanol-modifded silica nanoparticle was fabricated and employed as a framework to form‘‘soggy sand’’electrolyte along with 1-butyl-3-methylimidazolium tetrafluoroborate.‘‘Soggy sand’’and poly（vinyl...A kind of octanol-modifded silica nanoparticle was fabricated and employed as a framework to form‘‘soggy sand’’electrolyte along with 1-butyl-3-methylimidazolium tetrafluoroborate.‘‘Soggy sand’’and poly（vinylidene fluoride-hexafluoropropylene）composite electrolyte membranes were electrospun for the frst time.The properties of this membrane electrolyte have been evaluated by the mechanical test and electrochemical test.The Young’s modulus increased by 275%from 6.8 MPa to 25.5 MPa and the electrical conductivity increased to 7.6 10à5S/cm at 290.15 K when compared to pristine P（VdF-HFP）membrane electrolyte.The conductivity is 3.1 10à4S/cm at 323.15 K.展开更多
文摘Surface-enhanced Raman scattering （SERS） has emerged as an excellent analytical tool for the effective detection and fingerprint identification of various chemicals. Recently, significant progress has been made in the fabrication of SERS-active substrates using simple, inexpensive, and affordable methods. The full potential of universal SERS diagnostics will likely be realized with the development of approaches and devices capable of effectively detecting analytes on various surfaces as well as in multicomponent media. In addition, the combination of implantable or wearable SERS-active substrates and remote portable devices enables real-time diagnostics that ideally fit the concept of personalized medicine. In this paper, we summarize recent achievements in fabricating flexible SERS substrates made of cellulose paper, polymer membranes, and textile fibrous films. Emphasis is placed on the in-situ extraction and detection of various chemicals in real-world surfaces and complex media using flexible nanofibrous SERS platforms. The potential SERS applications and future perspectives in on-site diagnostics are also discussed.
基金financially supported by the National Natural Science Foundation of China(Nos.51303174,51321062,51233004,51390484,51273196,and 51203153)the Scientific Development Program of Jilin Province(No.20140520050JH)
文摘An electrospun poly（lactide-co-glycolide） （PLGA） membrane was prepared and used to perform the anti-adhesion of Achilles tendon. Throughout the experiments, the membrane showed an appropriate degradation rate, and the pH values of degradation media were maintained at around 7.4. Simultaneously, the excellent biocompatibility of the membrane in vitro and in vivo was confirmed by live/dead and histopathological analyses. Meanwhile, the membrane can reduce tendon adhesion significantly and promote functional recovery effectively. The encouraging results were further demonstrated by hematoxylin and eosin （H＆E）, and Masson＇s trichrome stainings, and type I collagen immunohistochemical analysis. It was concluded that the model treated with the electrospun PLGA membrane was significantly better with respect to the adhesion prevention and tissue repair than that without treatment. Considering the results of degradation and adhesion prevention efficacy, the electrospun PLGA membrane would be a great candidate for the prevention of postoperative tendon adhesion.
基金Supported by the National Natural Science Foundation of China(Nos.50273027,50573055,30828008)the Natural Science Foundation of Tianjin City,China(No.09JCZDJC18600)
文摘In order to encapsulate and controlled-release bioactive proteins,three fibrous membranes,i.e.,poly（L-lactide-co-glycolide）（PLGA）,hybrid PLGA and chitosan（H-PLGA/CS）,and core/shell PLGA/CS （C-PLGA/CS）,were produced by emulsion electrospinning,co-electrospinning and coaxial electrospinning,respectively.Bovine serum albumin（BSA） was selected as a model protein.The loading efficiency of BSA in the PLGA membrane was 1.56%,lower than those of H-PLGA/CS（5.98%） and C-PLGA/CS（4.80%）.BSA release profiles from the three membranes showed initial burst releases in the first 7 d and then sustained release for 28 d.Cumulative releases at the end of the releasing period,28 d,from the above three membranes were nearly 63%,88% and 94%,respectively,indicating that the introduction of chitosan and the core/shell fiber structure could enhance BSA release rate.In addition,all these electrospun membranes could retain their fibrous morphologies after in vitro release of BSA for 28 d.
文摘静电纺丝纳米纤维膜作为锂离子电池隔膜使用时具有优良的性能,但是由于纤维间抱合力较小,强度较低,其应用受到了极大限制。通过耐高温相PAN与低熔点相PVDF两种聚合物混纺,并经过适当的热压后处理,使PVDF部分熔融形成点粘结,制备PAN-PVDF复合纳米纤维膜,并测试其相关性能。发现在保留静电纺膜优良性能的前提下,其强度相对处理前提高了近10倍,并表现出良好的电化学性能:室温下离子电导率达到1.32×10-3S/cm,聚合物电解质分解电压高达5.24 V,界面阻抗仅为45Ω,0.2 C首次放电比容量高达152 m Ah/g,综合性能远优于美国CELGARD2400。
基金supported by National Key Basic Research Program of China, 973 Program (Nos. 2012CB932800 and 2011CB93570)
文摘A kind of octanol-modifded silica nanoparticle was fabricated and employed as a framework to form‘‘soggy sand’’electrolyte along with 1-butyl-3-methylimidazolium tetrafluoroborate.‘‘Soggy sand’’and poly（vinylidene fluoride-hexafluoropropylene）composite electrolyte membranes were electrospun for the frst time.The properties of this membrane electrolyte have been evaluated by the mechanical test and electrochemical test.The Young’s modulus increased by 275%from 6.8 MPa to 25.5 MPa and the electrical conductivity increased to 7.6 10à5S/cm at 290.15 K when compared to pristine P（VdF-HFP）membrane electrolyte.The conductivity is 3.1 10à4S/cm at 323.15 K.
