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早期直肠癌的外科治疗 被引量:4

Surgery for Early Rectal Cancer
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摘要 目的 探讨早期直肠癌手术方式的选择。方法 回顾性分析我院行手术治疗的早期直肠癌 (Ι期 ) 182例患者资料 ,其中行根治术 13 5例 ,行局部切除术 47例。结果  182例患者随访时间为 5~ 2 76个月 ,中位随访时间为 76个月。行直肠癌根治术者 5年生存率为 93 .1% ,局部切除术者为 91.7% (P >0 .0 5 )。T1期直肠癌行根治术者和局部切除者 5年生存率分别为 10 0 %和 94.4% (P >0 .0 5 ) ,T2 期患者分别为 92 .5 %和 83 .3 % (P >0 .0 5 )。T2 期直肠癌局部切除术者 5年局部复发率高于根治术 ,分别为 2 7.3 %和11.1% (P <0 .0 5 )。结论 早期直肠癌行局部切除治疗是一种安全、有效的手术方式 ,对于身体条件差、具有严重合并症的患者 ,可以作为首选的手术方式。 Objective To evaluate the methods of excision for patients with early rectal cancer. Methods A retrospective medical chart review was performed in 182 patients with early rectal carcinoma( stageΙ) who treated with surgery. 135 patients underwent radical surgery and 47 patients underwent local excision. Results The follow-up was 5-276 months (median 76). 5-year survival was 93.1% after radical surgery and 91.7% after local excision (P>0.05). In T 1 patients, 5-year survival was 100% after radical surgery and 94.4% after local excision (P>0.05) and in T 2 92.5% and 83.3% (P> 0.05), respectively. For T 2 tumors, 5-year local recurrence rate was 27.3% after local excision and 11.1% after radical surgery (P<0.05). Conclusions Local excision of early stage rectal cancer is safe and effective therapy, which can be used as primary surgical treatment for patients with serious complication.
出处 《中国医刊》 CAS 2004年第5期25-26,共2页 Chinese Journal of Medicine
关键词 直肠癌 治疗 外科手术 回顾性分析 rectal neoplasm radical surgery local excision
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参考文献5

  • 1Balani A, Turoldo A, Braini A, et al.Local excision for rectal cancer[J].J surg oncol, 2000, 74: 158-162. 被引量:1
  • 2Heriot AG, Grundy A, Kumar D, Preoperative staging of rectal carcinoma[J].Br J Surg, 1999,86: 17-28. 被引量:1
  • 3Benoist S, Panis Y, Martella L, et al.Local excision of rectal cancer for cure: should we always regard rigid pathologic criteria? [J].Hepato-Gastroenterology, 1998, 45: 1546-1551. 被引量:1
  • 4Banerjee AK, Jehle EC, Shorthouse AJ, et al.Local excision of rectal tumours[J].Br J Surg, 1995, 82:1165-1173. 被引量:1
  • 5Kim CJ, Yeatman TJ, Coppola D, et al.Local excision of T2 and T3 rectal cancers after downstaging chemoradiation[J].Ann Surg, 2001, 234:352-358. 被引量:1

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