摘要
目的:评价经肛门局部切除Ⅰ期低位直肠癌的疗效。方法:回顾性分析我院29例经肛门行局部切除术的Ⅰ期(T1-N0M0)直肠癌患者的资料(局部切除术组),其中T1期20例,T2期9例;以23例行根2治术的Ⅰ期直肠癌患者作为对照(根治术组,1期8例,2期15例)。对2组患者的并发症发生率、年复发TT5率、年存活率进行对比分析。结果:2组T1期5年生存率均为100%,2期5年存活率局部切除术组为5T88.9%,根治术组为100%,组比较差异无统计学意义(P>0.05)。T1期5年复发率局部切除术组为5.0%,2根治术组为0,T2期5年复发率分别为44.4%和6.7%,2期5年复发率2组比较差异显著(P=0.04)。局部T切除术组并发症发生率为0,根治术组为30.4%,2组比较差异显著(P=0.02)。结论:对于T1期直肠癌,经肛门局部切除是合理选择,而T2期直肠癌不宜单纯采用局部切除。
Objective：To evaluate the therapeutic effect of transanal local excision in the treatment of low rectal cancer in stage I.Methods：The data of 29 cases of low-set rectal cancer patients in stage（T1-N0M0）treated by transanal local excision（group A,20 cases of T1 patients and I 29 cases of T2 patients）were reviewed retrospectively,and the group of 23 cases with radical resec tion（group B,8 cases of T1 patients and 15 cases of T2 patients）.The 5-year survival rates,recur rence rates,and postoperative complications between the two groups were compared.Results：The 5-year survival rates were 100%（20/20）for T1 patients and 88.9%（8/9）for T2 patients in group A,and 100%（8/8）for T1 patients and 100%（15/15）for T2 patients in group B.There was no significantly statistical difference between the two groups（P0.05）.The recurrence rates were 5.0%（1/20）for T1 patients and 44.4%（4/9）for T2 patients in group A,and 0（0/8）for T1 patients,6.7%（1/15）for T2 patients in group B.There was no significant difference between two groups of T1 patients（P0.05）,but significant difference between the two groups of T2 patients（P=0.040.05）.The incidence of postoperative complications in group A was 0%（0/29）,which was significantly lower than that of 30.4%（7/23）in group B（P=0.010.05）.Conclusions：For T1 patients of low-set rectal cancer,transanal local excision is a reasonable choice.While For T2 patients,transanal local excision only is not suitable.
出处
《中国现代普通外科进展》
CAS
2010年第5期370-372,共3页
Chinese Journal of Current Advances in General Surgery
