摘要Gln(谷氨酰胺)近些年来受到广泛关注(Newsholme et al 1988),是机体内最丰富的非必需氨基酸,因测定Gln技术较复杂、不易研究,直至50年代Eangle等发现Gln是培养细胞分化增殖所必需的营养物质,才提出Gln可能具有重要而独特的代谢特性的概念(Ardawi MS 1998,Laeey J and Wilmore DW 1990).近几年来,在Gln的代谢、在肠外营养中的应用、对免疫功能的调节作用等方面都有了深入的研究(谭文军,2001).
3Newsholme E. A, Newsholme P, Curi R, Challoner M. A,Ardawi M. S. M, 1988. A role for muscle in immune system and its importance in surgery, trauma, sepsis and burns.Nutrition 4,261 ～ 268. 被引量：1
4Souba WW, Herskowitz K, Salloum RM et al, 1990: Gut glutamine metabolism [J]. JPEN, 14(4suppl): 45s. 被引量：1
5Newsholme E. A, Carrie A. L, 1994. Quantitative aspects of glucose and glutamine metabolism by intestinal cells. Gut35, Suppl. 1, S13 ～ S17. 被引量：1
6Pierzynowski SG. and Sjodin A. 1998: Perspectives of glutamine and its derivatives as feed additives for farm animals. Journal of Animal and Feed Sciences, 7,79～91. 被引量：1
9Alverdy JC, 1990: Effects of glutamine-supplemented diets on immunology of the gut [J].JPEN, 14(4suppl): 109s. 被引量：1
10Inoue Y, Grant J. P, Snyder JP, 1993 Effect of glutaminesupplemented total parenteral nutrition on recovery of small intestine after starvation atrophy. JPEN 17, 165～ 170. 被引量：1
3YOUNG V R,AJAMI A M.Glutamate:an amino acid of particular distinction[J].The Journal of Nutrition,2000,130:892S-900S. 被引量：1
4YOUNG V R,AJAMI A M.Glutamine:the emperor or his clothes[J].The Journal of Nutrition,2001,131(Suppl.9):2449S-2459S. 被引量：1
5SMITH R J,WILMORE D W.Glutamine nutrition and requirements[J].Journal of Parenteral and Enteral Nutrition,1990,14(Suppl.4):94s-99s. 被引量：1
6PIERZYNOWSKI S G,SJODIN A.Perspectives of glutamine and its derivatives as feed additives for farm animals[J].Journal of Animal and Feed Sciences,1998(7):79-91. 被引量：1
7CYNOBER L.Ornithine alpha-ketoglutarate in nutritional support[J].Nutrition,1991,7(5):313-322. 被引量：1
8HELTON W S,JACOBS D O,BONNER-WEIR S,et al.Effects of glutamine-enriched parenteral nutrition on the exocrine pancreas[J].Journal of Parenteral and Enteral Nutrition,1990,14(4):344-352. 被引量：1
9HELTON W S,SMITH R J,ROUNDS J,et al.Glutamine prevents pancreatic atrophy and fatty liver during elemental feeding[J].Journal of Surgical Research,1990,48(4):297-303. 被引量：1
10WU G,MEIER S A,KNABE D A.Dietary glutamine supplementation prevents jejunal atrophy in weaned pigs[J].The Journal of Nutrition,1996,126(10):2578-2584. 被引量：1
