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全髋关节置换术后并发应激性溃疡的多因素分析 被引量:4

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摘要 目的探讨全髋关节置换术后并发应激性溃疡的原因及相关危险因素。方法回顾分析396例首次行全髋关节置换术病例,选择性别、年龄、体重指数、病种、术前血红蛋白水平、术前是否有长期服用激素和消炎镇痛药、合并症以及手术时间、麻醉方式、假体固定方法、围手术期输血量、应用抑酸剂和抗栓治疗等指标进行统计。结果全髋关节置换患者中并发应激性溃疡18例,发生率为4.55%。患者年龄、体重指数、病种、血红蛋白水平、长期服用激素和消炎镇痛药、合并症和麻醉方式、假体固定方法、围手术期输血量以及进行抗栓治疗等因素与应激性溃疡的发生具有相关性(P【0.05)。结论全髋关节置术后并发应激性溃疡的主要危险因素为高龄、超重、股骨颈骨折、贫血、长期服用激素和消炎镇痛药、同时合并高血压和糖尿病、全麻、骨水泥固定及术后抗凝治疗。而抑酸治疗、硬外或腰麻和非骨水泥固定等因素可能为保护因素。
出处 《中国保健营养(下半月)》 2012年第5期1298-1300,共3页 China Health Care & Nutrition
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参考文献12

  • 1Abeer Zeitoun,Maya Zeineddine,Hani Dimassi.Stress ulcer prophylaxis guidelines:Are they being implemented in Lebanese health care centers?[J].World Journal of Gastrointestinal Pharmacology and Therapeutics,2011,2(4):27-35. 被引量:10
  • 2李志强,刘汝银,袁彦浩.双侧全髋关节同期置换术后应激性溃疡的防治[J].中医正骨,2006,18(4):57-57. 被引量:1
  • 3于皆平等主编..实用消化病学[M].北京:科学出版社,1999:1653.
  • 4Garcia Rodriguez LA,Cattaruzzi C,Troncon MG,et al.Risk of hopitalization for upper gastrointestinal tract bleeding associated with keterolac, other nonsteroidal anti-inflammatory drugs, calcium antagonists, and other antihypertensive drugs[].Archives of Internal Medicine.1998 被引量:1
  • 5Spirt M J.Stress-related mucosal disease: risk factors and prophylactic therapy[].Clinical Therapeutics.2004 被引量:1
  • 6Kantorova I,Svoboda P,Scheer P,et al.Stress ulcer prophylaxis in critically ill patients: a randomized controlled trial[].Hepato Gastroenterology.2004 被引量:1
  • 7ML Schubert.Gastric secretion[].Current Opinion in Gastroenterology.2008 被引量:1
  • 8JP Quenot,N Thiery,S Barbar.When should stress ulcer prophylaxis be used in the ICU?[].Current Opinion in Critical Care.2009 被引量:1
  • 9Yigiter M,Albayrak Y, et al.Influence of adrenal hormones in the occurrence and prevention of stress ulcers[].Journal of Pediatric Surgery.2010 被引量:1
  • 10Wendy N,Erber.Massive blood transfusion in the elective Surgical seeting[].Transfusion Apheresis Sci.2002 被引量:1

二级参考文献8

  • 1陈慧.外科应激性溃疡研究进展[J].泸州医学院学报,2005,28(1):89-91. 被引量:9
  • 2Suzuki H,Miura S,Imaeda H.Enhanced levels of chemilu minescence and platelet activating factor in unease positive gastric ulcers[J].Free Radoc Biol Med,1996,20:449. 被引量:1
  • 3Green RM;Flamm S.AGA technical review on the evaluation of liver chemistry tests,2002(04). 被引量:2
  • 4Spirt MJ,Stanley S.Update on stress ulcer prophylaxis in critically ill patientsCritical Care Nurse,2006. 被引量:1
  • 5Mutlu GM,Mutlu EA,Factor P.GI complications in patients receiving mechanical ventilation. Chest . 2001 被引量:2
  • 6Netzer P,Gaia C,Sandoz M,at al.Effect of repeated injection and continuous infusion of omeprazzole and ranitidine on intragas tric pH over 72 hours. The American journal of Gastroenterology . 1999 被引量:2
  • 7Cook D J,Reeve B K,Guyatt G H,et al.Stress ulcer prophylaxis in critically ill patients: Resolving discordant meta-analyses. The Journal of The American Medical Association . 1996 被引量:2
  • 8LL Manning-Dimmitt,SG Dimmitt,GR Wilson.Diagnosis of gastrointestinal bleeding in adults. American Family Physician . 2005 被引量:2

共引文献9

同被引文献40

  • 1Abeer Zeitoun,Maya Zeineddine,Hani Dimassi.Stress ulcer prophylaxis guidelines:Are they being implemented in Lebanese health care centers?[J].World Journal of Gastrointestinal Pharmacology and Therapeutics,2011,2(4):27-35. 被引量:10
  • 2黄仁伦.应激性溃疡发生机制研究进展[J].国际医药卫生导报,2006,12(22):120-122. 被引量:31
  • 3陈新谦,金有豫,汤光.新编药物学[M].第17版.北京:人民卫生出版社,2011:32-33. 被引量:501
  • 4Bez C, Perrottet N, Zingg T, et al. Stress ulcer prophylaxis in non-critically ill patients: a prospective evaluation of cur- rent practice in a general surgery department[ J]. J Eval Clin Pract,2013 , 19 ( 2 ) :374-378. 被引量:1
  • 5Craig DG, Thimappa R, Anand V, et al. Inappropriate utili- zation of intravenous proton pump inhibitors in hospital prac- tice-a prospective study of the extent of the problem and pre- dictive factors [ J ]. QJM,2010 , 103 (5) : 327-335. 被引量:1
  • 6Patrono C, Bachmann F, Baigent C,et al. Expert consensus document on the use of antiplatelet agents. The task force on the use of antiplatelet agents in patients with atherosclerotic cardiovascular disease of the European society of cardiology [J]. Eur Heart J, 2004,25(2) :166-181. 被引量:1
  • 7Cook DJ, Reeve BK, Guyatt GH, et al. Stress ulcer prophy-laxis in critically ill patients. Resolving discordant meta-ana- lyses [ J ]. JAMA, 1996,275 (4): 308 -314. 被引量:1
  • 8Lin PC, Chang CH, Hsu PI, et al. The efficacy and safety of proton pump inhibitors vs histamine-2 receptor antagonists for stress ulcer bleeding prophylaxis among critical care pa- tients : a meta-analysis [ J ]. Crit Care Med, 2010 , 38 ( 4 ) : 1197-1205. 被引量:1
  • 9Johnstone J, Nerenberg K, Loeb M. Meta-analysis: proton pump inhibitor use and the risk of community-acquired pneu- monia[J]. Aliment Phatmo~ol Ther,2010 ,31 ( 11 ) : 1165- 1177. 被引量:1
  • 10FDA . FDA Drugs Safety Communication:Possible increased risk of fractures of the hip, wrist, and spine with the use of proton pump inhibitom[ R]. 2010-O6-04. 被引量:1

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