摘要
目的:调查某院围术期预防性使用质子泵抑制剂的使用现状,评价使用合理性。方法:抽取某院2016年1—12月围术期预防使用质子泵抑制剂的病例共3798例,采用回顾性分析法从用药指征、用法用量、疗程、药物选择等方面评价预防用药的合理性。结果:预防用药的合理率为7.35%,不合理用药例次累计5214次。主要表现为:无指征预防用药2278例次(43.69%)、用法用量不适宜1696例次(32.53%)和疗程过长1190例次(22.82%)。结论:围术期预防使用质子泵抑制剂的不合理现象较为突出,亟待使用标准和规范来促进该类药物的合理使用。
Objective： Investigate the current status of preventive medication of proton pump inhibitors（PPIs） during perioperative period and analyze the rationality of PPIs for preventing stress ulcer. Methods： 3 798 cases preventively used PPIs between January and December 2016 were extracted.Then, the rationality of these drugs in the 3 798 cases was evaluated in terms of indications, usage and dosage, course of treatment and drug selection. Results： The overall rational rate of preventive medication was 7.35%, 5 214 cases of irrational drug use were counted. In these results above, the major problems were inappropriate indications（2 278, 43.69%）, improper usage and dosage（1 696, 32.53%） and excessive medication regimen（1 190, 22.82%）. Conclusion： Based on the survey results, irrational use of PPIs during perioperative period in our hospital is an outstanding problem and hospital needs to further strengthen the standardized the preventive use of the PPIs during perioperative period.
出处
《临床药物治疗杂志》
2017年第9期42-46,共5页
Clinical Medication Journal
关键词
质子泵抑制剂
围术期
应激性溃疡
合理用药
proton pump inhibitors
perioperative period
stress ulcer
rational drug use
