摘要
通过α-萘乙酰肼与芳酰异硫氰酸酯的亲核加成反应,制得1-(α-萘乙酰基)-4-芳酰基氨基硫脲衍生物(2a～21).2a～21在酸性条件下环化脱水为未知的2-芳酰氨基-5-(α-萘甲基)-1,3,4-噻二唑(3a～31).所得十二个新化合物的结构均经元素分析,IR,~1H-NMR和MS鉴定.
It presented the synthesis of 2-aroylamino-5-(a-naphthalenemthyl)-l, 3, 4-thiadiazoles (3a-31) by the acid catalytic cyclization of l-(a-naphthaleneacetyl)-4-aroylthiosemicarbazides (2a-21) which were prepared by the nucleophilic addition reaction of a-naphthaleneacetyl hydrazide and aroyl-isothiocyanide. Twelve new compounds were prepared and their strutures were characterized by means of elemental analysis, 'H-NMR, IR and MS.
出处
《西南师范大学学报（自然科学版）》
CAS
CSCD
1992年第4期476-481,共6页
Journal of Southwest China Normal University(Natural Science Edition)
关键词
酰基
氨基
硫脲
噻二唑
光谱分析
cylthiosemicarbazides
1. 3, 4-thiadiazole
preparation and spectral analysis
