摘要
目的 观察抑肽酶辅助治疗脑出血脑水肿的疗效及安全性。方法 收集脑出血患者 41例 ,分为 2组 ,抑肽酶治疗组 2 1例 ;对照组 2 0例。治疗前后进行神经功能评分 ,CT下测量水肿体积。结果 (1 )入院后 1、2、3周用欧洲脑卒中量表进行神经功能评分 ,抑肽酶治疗组分值高于对照组 (P <0 .0 5)。 (2 )水肿产生量治疗组少于对照组 (P <0 .0 5)。结论 脑出血急性期加用抑肽酶可以抑制脑水肿的形成 ,提高脑出血患者神经功能评分 。
Objective To observe the therapeutic effects of aprotinin on cerebral hemorrhage and cerebral edema. Methods 41 patients were divided into two groups:aprotinin treating group (21 cases)and control group(20 cases). The patients' neurologic function was marked according to the European Stroke Standards of Grading For Cerebral Attacking. The Volumes of edema were observed by CT in 10d through 14d after their attacks. Results The therapeutic effect on the aprotinin treating group was significantly better than that in the control group,while the producing of edema was significantly less than the control group. Conclusion Aprotinin can inhibit the formation of cerebral edema and improve neurologic function marks after attacks. It is better to use aprotinin simultaneously than to use mannitol only.
出处
《中风与神经疾病杂志》
CAS
CSCD
北大核心
2003年第3期233-234,共2页
Journal of Apoplexy and Nervous Diseases
