摘要
目的探讨心脑舒通胶囊(XNSTC)对颈动脉粥样硬化的治疗作用。方法 62例颈动脉粥样硬化病人,随机分为心脑舒通胶囊(XNSTC)组与阿斯匹林(ASP)组。XNSTC组32例给予心脑舒通胶囊治疗;ASP组30例内服ASP。两组病人均连续用药1年。治疗前后采用高频超声及彩色多普勒超声观察颈动脉结构及血流状态,并测定颈动脉内膜—中层厚度(IMT)、血脂及血液流变学各参数,与同期选择的19名健康人作对照分析。结果患者经心脑舒通胶囊(XNSTC)治疗1年,劲动脉IMT显著变薄(P <0.05),血清总胆固醇(TC)、三酰甘油(T G)、低密度脂蛋白固醇(LDL-C)显著下降(P均<0.01);ASP组患者颈动脉IMT、血脂(TC、TG、LDL-C)治疗前后差异无显著性(P均>0.05)。两组患者的血液流变学均有明显改善(P均<0.01)。治疗期间未见心脑舒通胶囊(XNSTC)明显毒副作用。结论心脑舒通胶囊可作为治疗颈动脉粥样硬化的一种有效而安全的药物。
Objective To explore the therapeutic effects for carotic arterial atherosclerotic diseases.Method 62 patients were divided into XNSTC group and Aspirin group randomly.32 patients of XNSTC group were given Xinnaoshutong Capsules treatment and 30 patients of ASP group were given ASP therapy.The two group received treatments for 1 year continuously.All patients accepted hi-frequency Ultrasonagraphy and Color Ultrasonagraphy to know about their cervical arterial structures and blood fluid conditions and index of IMT,blood lipids and hemorrheological data.At the same time,19 healthy contrast group were analyzed.ResultsAfter 1 year treatment with XNSTC,IMT of cervical artery became thinner(P<0.05)and concentrations of Total cholesterols(TC)、Triglycerides(TG)、Low-density lipids were decreased significantly(P<0.01).Patients with treatment of ASP,there were no significantly differences on the index of IMT、TC、TG、LDL(P>0.05).The hemorrheology of both groups were improved(P<0.01).During the period of treatment with XNSTC,no notably side-effects were observed.Conclusions XNSTC can use an effective and safe medication for Cervical atherosclerotic diseases.
出处
《首都食品与医药》
2019年第5期50-52,共3页
Capital Food Medicine
