摘要
目的:探讨中医西结合治疗脑梗死的疗效及对患者侧支循环建立的影响。方法:选取2017年6月至2019年1月北京市第二医院收治的脑梗死患者128例作为研究对象,按照随机数字表法分为对照组和观察组,每组64例。对照组患者应用常规西医治疗(依达拉奉注射液),观察组在对照组的基础上联合中医治疗(疏血通注射液),比较2组患者的治疗效果,及治疗前后神经功能缺损情况(NIHSS评分)、日常生活能力(Bathel评分)、血脂血液流变学及缺血区脑血流量。结果:观察组患者治疗总有效率为90.6%(58/64),高于对照组的75%(48/64),2组比较差异有统计学意义(P<0.05);治疗前,2组NIHSS评分、Bathel评分、血脂水平及血液流变学指标、缺血区脑血流量比较,差异均无统计学意义(P>0.05);治疗后,观察组NIHSS评分低于对照组、Bathel评分明显高于对照组(P<0.05);治疗后观察组各项血脂水平及血液流变学指标均优于对照组,观察组缺血区脑血流量高于对照组(均P<0.05)。结论:中西医结合治疗能有效提高脑梗死患者治疗效果,有利于提高患者神经功能及日常生活能力,改善患者血脂及血液流变学指标,有利于患者侧支循环的建立。
Objective: To explore the curative effects of Western medicine combined with traditional Chinese medicine on cerebral infarction and its influence on the establishment of collateral circulation in patients with cerebral infarction. Methods: A total of 128 patients with cerebral infarction admitted to Beijing Second Hospital from June 2017 to January 2019 were selected as research objects,and they were divided into an observation group and a control group according to the random number table method,with 64 cases in each group.Patients in the control group were treated with routine western medicine (edaravone injection),while patients in the observation group were treated with traditional Chinese medicine (Shuxuetong injection) on the basis of the control group.The therapeutic effect,neurological deficit (NIHSS score),daily living ability (Bathel score),blood lipid,hemorheology and cerebral blood flow in ischemic area before and after treatment were compared between the 2 groups. Results: The total effective rate of the observation group was 90.6%(58/64),higher than 75%(48/64) of the control group.There was significant difference between 2 groups ( P <0.05);before treatment,there was no significant difference in NIHSS score,Bathel score,blood lipid level,hemorheological index and cerebral blood flow in ischemic area between the 2 groups ( P >0.05);after treatment,the NIHSS score of the observation group was lower than that of the control group,and the Bathel score was significantly higher than that of the control group ( P <0.05).After treatment,the blood lipid level and hemorheological indexes in the observation group were better than those in the control group,and the cerebral blood flow in the ischemic area in the observation group was significantly higher than that of the control group ( P <0.05). Conclusion: Integrated traditional Chinese and Western medicine can effectively improve the therapeutic effects of cerebral infarction patients,help to improve the neurological function and daily living ability of pat
作者
晏蕾
欧云尉
马玲
Yan Lei;Ou Yunwei;Ma Ling(Department of Cardiovascular Internal Medicine,Beijing Second Hospital,Beijing 100031,China;Department of Neurology Surgery,Beijing Tiantan Hospital,Capital Medical University,Beijing 100050,China;Department of Critical Care Medicine,Fuxing Hospital,Capital Medical University,Beijing 100038,China)
出处
《世界中医药》
CAS
2019年第5期1251-1253,1257,共4页
World Chinese Medicine
基金
国家自然科学基金项目(81502150)
关键词
中西医结合治疗
脑梗死
疗效
侧支循环建立
Integrated traditional Chinese and western medicine
Cerebral infarction
Curative effect
Establishment of collateral circulation
