摘要
目的:探讨持续性静脉泵入奥曲肽治疗肠梗阻的临床效果。方法:2011年10月-2013年10月收治手术治疗肠梗阻患者120例,对其临床资料进行回顾性分析,并根据治疗方法的不同分成对照组和观察组,将奥曲肽皮下注射法治疗的患者归入对照组,每组60例;将采用持续性静脉泵入奥曲肽法治疗的患者纳入观察组,共60例,对比两组的治疗效果。结果:观察组治愈率93.33%,显著高于对照组的83.33%,且差异具有统计学意义(P<0.05)。观察组临床症状缓解率90%,肛门排气时间(3.05±1.17)d,显著优于对照组的73.33%和(5.1±2.21)d,差异均具有统计学意义(P<0.05)。两组均无显著的不良反应和肝肾功能损伤,差异不具有统计学意义(P>0.05)。结论:对肠梗阻患者采用持续性静脉泵入奥曲肽的方法进行可以有效缓解患者的临床症状,提高治愈率,促进患者康复,具有显著的治疗效果。
Objective:To investigate the clinical effect of continuous intravenous infusion of octreotide in the treatment of intestinal obstruction.Methods:120 patients with intestinal obstruction who was taken operation treatment were selected from October 2011 to October 2013.We retrospectively analyzed their clinical data.They were divided into the control group and observation group according to the different treatment.Patients who taken the subcutaneous octreotide injection therapy as the control group,and a total of 60 cases in this group.Patients who received continuous intravenous infusion of octreotide therapy as the observation group with 60 cases in it.Then we compared the treatment effect of two groups.Results:The cure rate of the observation group was 93.33%,significantly higher than 83.33% of the control group,and the difference was statistically significant(P<0.05).The clinical symptom relief rate of the observation group was 90%,and anal exhaust time was(3.05±1.17)d,significantly better than the control group with 73.33% and(5.1 ± 2.21)d respecativily,and the differences were statistically significant(P<0.05).There were no significant adverse reactions and the function of liver and kidney damage in two groups,and the differences were statistically significant(P>0.05).Conclusion:Continuous intravenous infusion of octreotide in the treatment of patients with intestinal obstruction can effectively relieve the clinical symptoms,and it also can improve the cure rate and promote the rehabilitation of patients,so we can summarized that it has an obvious curative effect on intestinal obstruction.
关键词
持续静脉泵入
奥曲肽
肠梗阻
回顾性分析
Continuous intravenous pumping
Octreotide
Intestinal obstruction
A retrospective analysis
