摘要
目的 :分析奥曲肽治疗恶性肠梗阻的有效性及安全性。方法 :选取2016年3月—2017年8月我院收治的恶性肠梗阻患者85例为研究对象,按治疗方法不同分为两组,对照组(42例)给予常规疗法;观察组(43例)在对照组基础上加用奥曲肽(1 mg,tid)治疗,观察两组治疗效果及安全性。结果 :观察组呕吐、恶心、腹胀、腹痛消失时间、肛门排气时间与排便改善时间短于对照组,差异有统计学意义(P <0.05);两组不良反应发生率比较,差异无统计学意义(P> 0.05)。结论:奥曲肽治疗恶性肠梗阻可有效改善临床症状,提高有效性,且安全性好。
Objective: To analyze the efficacy and safety of octreotide in the treatment of malignant intestinal obstruction. Methods: 85 patients with malignant intestinal obstruction admitted to our hospital from March 2016 to August 2017 were selected as subjects investigated and divided into two groups according to different treatment methods. The patients in the control group (42 cases) received conventional therapy, and the patients in the observation group (43 cases) were treated with octreotide (1 mg, tid) on the basis of the control group. The therapeutic effect and safety in the two groups were observed. Results: The disappearance time of vomiting, nausea, abdominal distention and abdominal pain, anal exhaust time and defecation improvement time in the observation group were significantly shorter than those in the control group (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion: Octreotide can effectively improve clinical symptoms and improve effectiveness in the treatment of malignant intestinal obstruction, and is safe and is an ideal treatment plan.
作者
王安连
Wang An-lian(Department of General Surgery,the Second People’s Hospital of Kaifeng City,Henan Kaifeng 475000,China)
出处
《中国执业药师》
CAS
2018年第11期117-119,共3页
China Licensed Pharmacist
关键词
奥曲肽
恶性肠梗阻
有效性
安全性
Octreotide
Malignant Intestinal Obstruction
Effectiveness
Safety
