摘要
目的:探讨老年肠梗阻患者选择经鼻型肠梗阻导管联合生长抑素治疗所取得的临床效果。方法:回顾性分析2019年6月-2022年5月宜春市人民医院收治的82例老年肠梗阻患者的临床资料,根据患者及其家属自己选择的是否行肠梗阻导管治疗分为两组。观察组46例,采取经鼻型肠梗阻导管减压联合生长抑素治疗;对照组36例,采取传统鼻胃管减压联合生长抑素治疗。比较两组疗效、相关临床指标、不良反应发生情况及炎症指标。结果:观察组总有效率、24 h胃肠减压量、24 h内腹围缩小量均高于对照组(P<0.05)。观察组液气平面消失时间早于对照组,不良反应发生率低于对照组(P<0.05)。治疗前,两组C反应蛋白(CRP)、白细胞介素-6(IL-6)与肿瘤坏死因子-α(TNF-α)水平比较,差异均无统计学意义(P>0.05);治疗后,两组CRP、IL-6、TNF-α水平均低于治疗前,且观察组均低于对照组(P<0.05)。结论:对老年肠梗阻患者皮下注射生长抑素,并使用经鼻型肠梗阻导管进行减压治疗,可显著缓解患者肠梗阻症状,减轻炎症反应并促进胃肠功能恢复,有效预防不良反应,具有临床推广应用价值。
Objective:To explore the clinical effects of transnasal intestinal obstruction catheter combined with somatostatin therapy on elderly patients with intestinal obstruction.Method:The clinical data of 82 elderly patients with intestinal obstruction who were admitted to Yichun People’s Hospital from June 2019 to May 2022 were retrospectively analyzed,and the patients were divided into two groups according to whether the patients and their families chose to undergo intestinal obstruction catheter therapy.46 patients in the observation group were treated with transnasal intestinal obstruction catheter decompression combined with somatostatin,and 36 patients in the control group were given traditional nasogastric tube decompression combined with somatostatin.The clinical efficacy,related clinical indicators,incidence rates of adverse reactions and the inflammatory indicators were compared between the two groups.Result:The total effective rate,amount of gastrointestinal decompression within 24 hours and abdominal circumference reduction within 24 hours in the observation group were higher than those in the control group(P<0.05).The disappearance time of air-liquid plane in the observation group was earlier than that in the control group,and the incidence of adverse reactions in the observation group was lower than that in the control group(P<0.05).Before treatment,there were no significant differences in the levels of C reactive protein(CRP),interleukin-6(IL-6)and tumor necrosis factor-α(TNF-α)between the two groups(P>0.05).After treatment,the levels of CRP,IL-6 and TNF-αin both groups were lower than those before treatment,and those in the observation group were lower than those in the control group(P<0.05).Conclusion:For elderly patients with intestinal obstruction,subcutaneous injection of somatostatin and decompression therapy with transnasal intestinal obstruction catheter can significantly relieve the intestinal obstruction symptoms,alleviate the inflammatory response,promote the recovery of gastrointestinal
作者
郑伟
江福生
欧阳锋
王樱花
胡军
ZHENG Wei;JIANG Fusheng;OUYANG Feng;WANG Yinghua;HU Jun(Yichun People’s Hospital,Jiangxi Province,Yichun 336000,China)
出处
《中国医学创新》
CAS
2022年第27期29-32,共4页
Medical Innovation of China
基金
宜春市科技计划项目(JXYC2020KSA018)。
关键词
经鼻型肠梗阻导管
生长抑素
胃肠减压
肠梗阻
Transnasal intestinal obstruction catheter
Somatostatin
Gastrointestinal decompression
Intestinal obstruction
