摘要
目的:观察苦参碱联合化疗治疗进展期胃癌的疗效。方法:收治进展期胃癌患者80例,随机分成观察组和对照组,每组40例,其中对照组给予单纯的化疗,而观察组给予苦参碱联合化疗。观察期为2周,并对所得结果进行整合评价。结果:治疗组的有效率55%,对照组的有效率47.5%。差异无统计学意义(P>0.05)。在生活质量方面,治疗组提高率40%,对照组提高率25%,差异具有统计学意义(P<0.05)。两组发生不良反应的概率差异有统计学意义。结论:用苦参碱联合化疗的方法治疗进展期胃癌不仅能提高患者的生活质量,还能减轻化疗的不良反应。对于进展期胃癌的患者有卓越的疗效。
Objective:To observe the therapeutic effect of matrine combined with chemotherapy for advanced gastric cancer. Methods:Patients with advanced gastric cancer were treated 80 patients were randomly divided into observation group and control group 40 cases,in which the control group received chemotherapy alone,while the observation group were given matrine chemotherapy.Observation period of two weeks,and to integrate the results of the evaluation.Results:The response rate of 55% in the control group and 47.5% efficiency.The difference was not significant(P>0.05),with statistical significance.In terms of quality of life,the treatment group improved 40%,increase the rate of 25% in the control group, the difference was statistically significant(P<0.05).The probability of the occurrence of side effects between the two groups was significant.Conclusion:The method matrine chemotherapy treatment of advanced gastric cancer can not only improve the quality of life of patients,but also reduce the toxicity of chemotherapy.For patients with advanced gastric cancer have superior efficacy,and therefore deserve promotion in clinical practice.
关键词
苦参碱
进展期胃癌
化疗
Matrine
Advanced gastric cancer
Chemotherapy
