摘要
本实验研究了黄芪多糖对肉鸡脾淋巴细胞转化率及细胞内信息分子 -一氧化氮 (NO)、Ca2 + 及 c AMP、c GMP的影响。发现黄芪多糖能剂量依赖性促进脾淋巴细胞转化率及细胞内 NO、Ca2 + 浓度 ;当作用时间为 2 0 min时 ,4 0 μg/ ml黄芪多糖能增加 c AMP浓度 ,降低 c GMP浓度 (P<0 .0 1) ;而当作用时间为 6 0 m in,对 c AMP和 c GMP浓度无显著影响。以上结果提示 ,黄芪多糖能显著提高脾淋巴细胞免疫功能 ,其作用是通过改变细胞内信息传导实现的。
This research was conducted to study the effect of astragalan on splencytes proliferation and signal molecule like NO,Ca^(2+),cAMP and cGMP. The results showed that astragalan increased splencytes proliferation and the contents of NO and Ca^(2+) in similar dose dependent manner. It increased cAMP but decreased cGMP content when the treatment time was 20 min, but had no effect when the treatment time was 60 min.
出处
《中国兽医杂志》
CAS
北大核心
2003年第10期11-14,共4页
Chinese Journal of Veterinary Medicine
