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CpG-DNA活性的影响因素 被引量:1

CpG ODNs' Influence on Tdomeraseactivity,Cell Cycle and Apoptosis in Tumor Cells
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摘要 细菌DNA疫苗的发现引发了对免疫刺激序列CpG-DNA的研究。CpG-DNA被细胞吞噬后与胞内受体结合,引发信号转导,产生免疫应答,从而发挥抗病毒、抗肿瘤免疫作用。针对该过程中影响CpG-DNA活性的诸多因素,从核心结构、骨架结构及信号转导等进行综述,希望对合理有效的DNA疫苗的构建有所帮助。
出处 《微生物学杂志》 CAS CSCD 2003年第4期45-47,共3页 Journal of Microbiology
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