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乳腺癌患者癌组织、血清miR-17-5p水平变化及意义 被引量：5

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摘要 目的观察乳腺癌患者癌组织、血清miR-17-5p水平变化、分析其临床意义。方法乳腺癌患者30例,分别取其癌组织及相应癌旁组织;另选乳腺癌患者60例、健康女性体检者50例,分别取其外周血。采用实时荧光定量PCR法检测乳腺癌组织及血清中的miR-17-5p。结果乳腺癌组织miR-17-5p表达低于癌旁组织,乳腺癌患者血清miR-17-5p低于健康女性体检者,P均<0.05。结论乳腺癌患者癌组织、血清miR-17-5p均降低,其水平检测有助于乳腺癌的诊断。
作者 魏倩 张鹏
机构地区 天津医科大学肿瘤医院
出处 《山东医药》 CAS 北大核心 2015年第16期54-55,共2页 Shandong Medical Journal
关键词 乳腺肿瘤 微小RNA 肿瘤标记物 miR-17-5p
分类号 R737.9 [医药卫生—肿瘤]
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参考文献13

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共引文献1019

同被引文献34

引证文献5

二级引证文献29

山东医药
2015年 第16期

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