摘要
目的:探讨亚洲型和西方型多发性硬化(multiplesclerosis,MS)多形式脑诱发电位的差异。方法:对19例亚洲型和24例西方型MS患者进行了视觉诱发电位(visualevokedresponse,VEP)、脑干听觉诱发电位(brain-stemauditorye-vokedpotential,BAEP)和躯体感觉诱发电位(somatosensoryevokedpo-tential,SEP)的综合研究,并对两者的临床特点进行了比较。结果:亚洲型多发性硬化发病年龄犤(35±12)岁犦明显高于西方型犤(27±11)岁犦(t=2.3378,P<0.05)。EDSS评分在亚洲型MS(5.3±2.3)也明显高于西方型(3.8±2.1)(t=2.2304,P<0.05)。亚洲型MS的VEP异常率(89%)显著高于西方型(54%)(χ2=4.7053,P<0.05),而BAEP异常率低(42%)显著低于西方型(71%)(χ2=70.4663,P<0.001)。结论:亚洲型和西方型是多发性硬化的两种不同的临床亚型。
AIM:To explore the dif fe rences of multim odality brain evoked potentials between Asian and Western types of mu ltiple sclerosis(MS ).METHODS:Visual evoked potentials(VEPs ),brai nstem auditory evoked potentials(BAEPs )and somatosensory evoked potentials(S EPs )were em-ployed in 19patients with Asian type and 24patients with West ern type of MS.Clinical features were also comp ared between two types of MS.R ESULTS:Age at onset in Asian type of MS was(34.9±12.1)years,signifi cantly higher than that in We stern type of MS [(26.8±10.6)years(t =2.3378,P<0.05)].The expanded disability status scale(EDSS)sco res in Asian type of MS (5.3±2.3)were also markedly higher than those i n Western type of MS (3.8±2.1)(t=2.2304,P<0.05).The ab -normal rate of VEP in Asian type of MS (89%)was significantly higher than that in Western type of MS (54%)(χ 2 =4.7053,P<0.05),while the abnormal rate of BAEP(42%)was markedly lower than that in Weste rn type of MS (71%)(χ 2 =70.4663,P<0.001).
出处
《中国临床康复》
CSCD
2003年第22期3062-3063,共2页
Chinese Journal of Clinical Rehabilitation
基金
河南省自然科学基金资助项目(0211044300)~~
