摘要
对２１例多发性硬化患者和２３例健康志愿者进行了韦氏成人智力量表测查和体感刺激诱发的事件相关脑诱发电位研究。结果表明，多发性硬化患者可出现不同程度的智能障碍，其中语言智商（３８％）、操作智商（４８％）和全量智商（３３％）在边界以下。本组患音表现为皮层下痴呆的特征。其认知电位Ｐ３００的潜伏期与对照组相比明显延长（Ｐ＜０．００１），波幅明显降低（Ｐ＜０．００１）
patients with multiple sclerosis(MS)and 23 hcalthy velunteers were subjected to WAIS-RC test and sensory event related potential study.The results indicated that MS patients had somc degree of intclligence disturbance,the ratc of thosc,whose VIQ,PIQor FIQ lower than 70一79 were 38%,48% or 37% respectively.MS patients showed charac -terasticx of subcortical dementia,the latency of cognitive P300 in them wds prolongcd significantly and the amplitude markedly lowerd as compared to controls'. Event relatcd potential P300 may be a predictor of reeognition impain ments in MS.
出处
《中国心理卫生杂志》
CSSCI
CSCD
北大核心
1996年第3期122-123,共2页
Chinese Mental Health Journal
关键词
多发性硬化
智能障碍
事件相关电位
multiple sclerosis, intelligence disturbance, event-related potential.
