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首发脑卒中患者的P300电位研究 被引量:3

Study on P300 potentials in patients with first cerebral stroke
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摘要 目的 探讨急性期脑卒中病人的P30 0电位变化 ,寻求判断此类患者认知功能的客观指标。方法 对 6 0例单一首发病灶的脑卒中病人和 6 2位健康者分别进行了P30 0电位测定 ,并将结果加以比较。结果 脑卒中组P30 0电位成分中N2 、P3 波潜伏期延长 ,P3 波幅降低 ,与对照组相比差异存在显著性 (P <0 0 5 ) ,而N1、P2波潜伏期两组相比差异未见显著性 (P >0 0 5 )。结论 P30 0电位对判定脑卒中患者的认知状况以及制定合理的治疗方案有重要的临床价值。 Objective To explore the change of P300 potentials in first cerebral stroke patients,and to find the objective index in judging the cognition in these patients.Methods P300 potentials test was used for sixty patients with their first episode of single loci stroke and sixty-two healthy people.The results were compared in the two groups.Results Latency periods of N 2 and P 3 of P300 potentials in cerebral stroke group were longer than those in the controls,the amplitude of P 3 of P300 potentials in cerebral stroke group was lower than that in the controls.There was significant difference between the two groups(P<0.05).Latency of N 1 and P 2 of P300 potentials was not significantly different between the two groups(P>0.05).Conclusion P300 potentials can reflect the cognition in cerebral stroke patients,which has remarkable clinical value in making reasonable treatment plan.
出处 《中国实用内科杂志》 CAS CSCD 北大核心 2004年第9期550-551,共2页 Chinese Journal of Practical Internal Medicine
基金 河南省高校青年骨干教师资助项目 ( 2 0 0 1162 )
关键词 脑卒中 P300电位 测定 急性期 诊断 Cerebral stroke P300 potentials
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  • 1Hom J,Reitan RM.Generalized cognitive function after stroke.J Clin Exp Neuropsychol,1990,12(5):644-653 被引量:1
  • 2张明岛,陈兴时等编著..脑诱发电位学[M].上海:上海科技教育出版社,1995:497.
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