摘要
以三七茎叶浸膏粉为主要原料及用可溶性淀粉、麦芽糊精、柠檬酸、羧甲基纤维素等为辅料,用浓度为80%的乙醇做润湿剂,单因素实验结果是三七茎叶浸膏粉:可溶性淀粉:麦芽糊精:羧甲基纤维素为1:0.1:0.1:0.05的比例制成三七茎叶颗粒饮片颗粒分布均匀、色泽均匀、硬度好、溶化性好,柠檬酸比例为1:0.08时,制得的颗粒口味适中,完全溶解,沉淀少;单一辅料的抗吸湿性没有混合辅料的抗吸湿性好,混合辅料以三七茎叶浸膏粉:可溶性淀粉:羧甲基纤维素的配比为1:0.5:0.05制成的颗粒抗吸湿性好,稳定性实验进一步证明该比例的抗吸湿性好,制成的样品经包装后稳定。
The extract powder of notoginseng stem and leaf as main raw materials, using soluble starch,maltodextrin, citric acid, carboxymethyl cellulose as auxiliary materials, using 80% ethanol as a wetting agent. The optimum molding process by a single factor experiment was notoginseng stem and leaf extract powder: soluble starch: maltodextrin: carboxymethyl cellulose is 1:0.1:0.1:0.05 ratio to make notoginseng stem and leaf granules, the particles are evenly distributed, evenly colored, good in hardness and good in melting. When the ratio of citric acid is 1:0.08, the prepared granules have moderate taste, complete dissolution and less sedimentation. The anti-hygroscopicity of single excipients is not as good as that of mixed adjuvant, and the mixed excipients are prepared with notoginseng stem and leaf extract powder: soluble Starch: carboxymethyl cellulose by 1:0.5:0.05 ratio to make granules with good anti-hygroscopicity. In addition, the stability test further proves that this ratio is good in hygroscopicity, and the prepared sample can be stably maintained after being packaged.
作者
周家明
韦祖茴
陈雪娇
马妮
赵爱
冯光泉
王朝梁
ZHOU Jia-ming;WEI Zu-hui;CHEN Xue-jiao;MA Ni;ZHAO Ai;FENG Guang-quan;WANG Chao-liang(Wenshan Sanqi Research Institute,Wenshan University,Wenshan,Yunnan 663099,China;School of Chemistry and Engineering,Wenshan University,Wenshan,Yunnan 663099,China)
出处
《人参研究》
2019年第1期26-30,共5页
Ginseng Research
基金
云南省高校工程研究中心建设计划资助项目
关键词
三七茎叶
颗粒饮片
可溶性淀粉
羧甲基纤维素
成型性
吸湿性
Notoginseng stem and leaf
Granulated slices
Soluble starch
Carboxymethyl cellulose
Formability
Hygroscopicity
