摘要
目的分析糖尿病合并尿路感染的病原菌分类及耐药情况,为临床经验性使用抗生素提供参考。方法选取医院2015年1月-2017年12月住院的糖尿病患者2 182例的尿液标本,回顾性分析细菌培养及药敏情况。结果 2 182例患者中尿液细菌培养阳性率为5.50%(120/2 182),革兰阴性菌占83.33%(100/120),其中大肠埃希菌占67.00%;革兰阳性菌占16.67%(20/120)。大肠埃希菌、肺炎克雷伯菌等致病菌对哌拉西林/他唑巴坦、头孢替坦、阿米卡星、亚胺培南等抗生素敏感,对氨苄西林、左氧氟沙星、环丙沙星等抗菌药物普遍耐药。结论糖尿病合并尿路感染患者的主要致病菌为革兰阴性杆菌,其中大肠埃希菌占首位。哌拉西林/他唑巴坦、头孢替坦、阿米卡星、亚胺培南等可作为糖尿病合并尿路感染患者治疗的敏感药物。
Objective To analyze the results of bacteria culture and microbial sensitivity test of urine of diabetes mellitus(DM)patients hospitalized in the hospital with urinary tract infection in order to provide reference for the rational use of antimicrobial drugs.Methods The results of bacteria culture and microbial sensitivity test of the urine samples from 2 182 DM inpatients during January 2015 and December 2017 were retrospectively analyzed.Results The positive rate of bacterial culture was 5.50%(120/2 182)for the 2 182 DM patients,the ratio of gram-negative bacteria was 83.33%(100/120),in which the total constituent ratio of escherichia coli was 67.00%,the ratio of gram-positive bacteria was 16.67%(20/120).escherichia coli and klebsiella pneumoniae were sensitive to piperacillin/tazobactam,cefotetan,amikacin,and imipenem,and resistant to ampicillin,levofloxacin,and ciprofloxacin.Conclusion The main pathogenic bacteria that cause urinary tract infection in DM patients is gram-negative bacteria,escherichia coli is the first,piperacillin/tazobactam,cefotetan,amikacin and imipenem are antibacterial drugs in treatment of DM patients with urinary tract infection.
作者
崔焕焕
CUI Huanhuan(Department of Endocrinology,Huishan People's Hospital of Wuxi,Jiangsu Province,Wuxi 214000,China)
出处
《临床合理用药杂志》
2019年第16期25-26,共2页
Chinese Journal of Clinical Rational Drug Use
关键词
糖尿病
尿路感染
病原菌
耐药性
Diabetes mellitus
Urinary tract infections
Pathogenic bacteria
Drug resistance
