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乙型肝炎病毒血清标志物组合模式的探讨 被引量:4

Investigation of hepatitis B virus serological markers models
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摘要 目的探讨不同的乙肝病毒血清标志物的组合模式。方法对住院患者共8 151份血清标本,采用化学发光法(CMIA)进行乙肝病毒血清标志物检测,分析结果并探讨多种不同组合模式。结果乙肝病毒血清标志物组合模式共有18种,其中最常见的4种模式,即模式1(全阴性)、模式2(抗-HBs+)、模式3(抗-HBs+、抗-HBc+)、模式4(抗-HBs+、抗-HBe+、抗-HBc+)所占比例,分别为24.6%、23.0%、20.3%和12.9%,同时也发现了一些少见模式,且HBs Ag阳性的病毒携带者比例较高(11.3%)。结论住院患者的乙肝病毒血清标志物组合模式较为复杂,且病毒携带者比例较高,分析HBV各种血清学模式可以获得有价值的临床诊疗信息,各种组合模式的探讨对HBV感染的预防、治疗、预后判断意义重大。 Objective To investigate the different models of HBV serological markers. Methods The HBV serological markers of 8151 serum samples being from the patients in our hospital during June 2012 to June 2013 were detected by chemiluminescence and the results were analyzed to explore a variety of different models. Results The HBV serum markers combined mode,a total of 18 species,of which the most common four modes: Mode 1( all negative),Mode 2( anti- HBs +),Mode 3( anti- HBs +,anti- HBc +),Mode 4( anti- HBs +,anti- HBe +,anti- HBc +) accounted for 24. 6%,23. 0%,20. 3% and 12. 9%. And there were also some unusual patterns. Conclusion There are many HBV models in patients. Therefore,it is necessary to emphasis on the detection of hepatitis B virus in hospital and strengthens prevention and control measures,controlling the spread of the virus within and outside the hospital.
出处 《宁夏医学杂志》 CAS 2015年第4期338-339,共2页 Ningxia Medical Journal
关键词 乙型肝炎病毒 乙型肝炎病毒血清标志物 化学发光法 感染模式 HBV HBV serum markers Chemiluminescence The pattern of infection
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