摘要
目的观察湖南衡阳地区人群的乙型肝炎标志物(HBV markers,HBV-Ms)分布,了解该地区人群乙型肝炎的免疫状况。方法以酶联免疫吸附试验(enzyme linked immunosorbent assay,ELISA)对2462例血清标本进行乙肝病毒表面抗原(HBsAg)、乙肝病毒表面抗体(HBsAb)、乙肝病毒e抗原(HBeAg)、乙肝病毒e抗体(HBeAb)、乙肝病毒核心抗体(HBcAb)检测。分析乙型肝炎标志物不同模式在人群中所占的比率,及主要模式在年龄段和性别的分布状况。结果本组资料的分类统计呈现20种不同的HBV-M模式,其中五项全阴、单独HBsAb阳性和小三阳(HBeAg、HBeAb、HBcAb)是本地区人群HBV感染的主要模式,在不同的年龄段中均有不同分布,且以男性为主。结论湖南衡阳地区人群HBV-M呈现多样性组合模式,临床应高度重视HBV-M的变异组合。
Objective To observe the distribution of hepatitis B virus（HBV） markers（HBV-Ms）,and understand the immune status of HBV infection in Hengyang Hunan.Methods HBV surface antigen（HBsAg）,HBV surface antibody（HBsAb）,HBV e antigen（HBeAg）,HBV e antibody（HBeAb） and HBV core antibody（HBcAb） were tested in 2462 serum samples by enzyme-linked immunosorbent assay（ELISA）.The ratios of HBV-M modes in the studied crowd,and the distribution of these modes in the groups of different ages and genders were analyzed.Results Twenty different HBV-M modes were detected in the present materials.All negative,HBsAb positive and HBsAg-HBeAb-HBcAb positive were the main modes of HBV infection.These modes had different distributions in groups of different ages and most infected subjects were males.Conclusion HBV-Ms in Hengyang district of Hunan province exhibits diversity and complexity.Much attention should be paid to the abnormal modes in clinic.
出处
《华南国防医学杂志》
CAS
2011年第6期498-499,517,共3页
Military Medical Journal of South China
