摘要
目的 评估农村人群中幽门螺杆菌 (Hp)感染在家庭内传播的比率以及家庭相关因素对其的影响。方法 通过抗Hp IgG抗体确定Hp感染率 ,对生姜产地进行以家庭为单位的居民Hp感染情况调查。 结果 Hp总的感染率为 43 .0 9% ,双亲感染家庭的儿童Hp感染率为 42 .0 0 % ,显著高于单亲感染家庭 ( 31.5 8% )和双亲未感染家庭儿童的感染率 ( 2 1.43 % ) ,P <0 .0 5。随着共同生活居住人口的增加 ,儿童Hp感染率也随之上升 (P <0 .0 5 ) ,家庭成员中喜食生姜者所占比例越高 ,儿童Hp感染率越低 ,呈负相关关系 (x2 =7.0 4,P <0 .0 5 )。结论 在一个开放的人群中 ,Hp感染呈现明显的家庭聚集现象 ,密切接触可增加儿童Hp感染机会。Hp感染机会受人口密度、居住条件、饮食习惯等因素的影响。喜食生姜对预防Hp传播有一定的作用。
Objective To assess the intrafamilial transmission of Helicobacter pylori(Hp)in the farming population and the role of a family's relevant factors.Methods An epidemiological survey on Hp infection based on family unit was performed in Ginger planting area. Hp infection was confirmed by presence of IgG antibodies against Hp.Results The overall Hp infection rate was 43.09%. Children belonging to the families with both parents infected had a significantly higher infection rate (42.00%) than those from families with only one (31.58%) or no parent (21.43%) infected (χ2=6.13,P< 0.05),The Hp infection rate in children increased with the population living together (χ2=6.18,P<0.05). The infection rate of children in the families of high Ginger consumption was lower than that in other families(χ2=7.04,P<0.05 ).Conclusion In an open population,Hp infection rate reveals an obvious familial clustering,close personal contact of family members increases the chance to infect Hp. Population density, housing conditions, dietary habits and so on might play a role in Hp infection.There're some obvious effects on preventing Hp infection because of the consumption of Ginger.
出处
《临床内科杂志》
CAS
北大核心
2003年第2期72-73,共2页
Journal of Clinical Internal Medicine
基金
该课题受福建省宁德市自然科学基金项目资助 (352 2Z
课题编号 0 1 2 0 )
关键词
幽门螺杆菌感染
生姜产地
流行病学
家庭聚集性
相关因素
感染率
Hplicobacter pylori infection/epidemiology
Ginger
Hplicobacter pylori infection/prevention and control
