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一种新的T细胞共刺激分子——4-1BB 被引量:2

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摘要 4 1BB是一种新发现的T细胞共刺激分子 ,属于TNFR NGFR超家族成员 ,近年来发现它在T淋巴细胞的活化、增殖、分化及凋亡等诸多方面发挥了重要的生物学功能。 4 1BB介导的活化信号主要是通过TPKp5 6 lck和TRAF的途径转导入胞内。本文拟就 4 1BB的有关问题作一综述。
作者 钱峰
出处 《国外医学(免疫学分册)》 2003年第2期76-78,共3页 Foreign Medical Sciences(Section of Immunology Foreign Medical Sciences)
基金 安徽省教育厅自然科学基金资助项目 (No .2 0 0 1kj168)
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