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妊娠期甲亢患者血清甲状腺功能和免疫含量变化及其临床意义 被引量:8

Changes of serum thyroid function and immune contents in patients with hyperthyroidism during pregnancy and its clinical significance
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摘要 目的 :探讨妊娠期甲亢患者血清甲状腺免疫含量及甲状腺功能的相关变化,为临床及早诊断与治疗提供依据。方法 :选择60例妊娠期甲亢患者为观察组,同期90例妊娠期非甲亢患者为对照组。结果 :妊娠早期,观察组患者T4、T3及TRAb阳性率高于对照组,差异存在统计学意义。妊娠中期,观察组患者T4、T3及TRAb阳性率均高于对照组,FT4及FT3低于对照组,差异存在统计学意义。妊娠晚期,观察组患者T4、T3高于对照组,FT4及FT3低于对照组,差异存在统计学意义。结论 :妊娠期甲亢患者血清甲状腺免疫含量及甲状腺功能在妊娠早、中、晚期均存在明显的改变,临床工作中应该定期检查以早期诊断和治疗。 Objective To investigate the changes of serum thyroid immune function and thyroid function in patients with hyperthyroidism during pregnancy, To provide evidence for clinical early diagnosis and treatment. Methods 60 cases of hyperthyroidism in pregnancy were selected as the observation group, The control group of 90 patients with non hyperthyroidism during pregnancy. Results The positive rate of T4, T3 and TRAb in the observation group was higher than that in the control group, The difference was statistically significant. The positive rate of T4, T3 and TRAb in the observation group were higher than those in the control group, FT4 and FT3 were lower than the control group, The difference was statistically significant. In the late pregnancy, T4 and T3 in the observation group were higher than those in the control group, FT4 and FT3 were lower than the control group, The difference was statistically significant. Conclusion The serum levels of thyroid immune and thyroid function in the early, middle and late stage of pregnancy in patients with hyperthyroidism were significantly changed, Early diagnosis and treatment should be regularly checked in clinical work.
作者 余显霞
出处 《湖南师范大学学报(医学版)》 2017年第1期171-172,共2页 Journal of Hunan Normal University(Medical Sciences)
关键词 甲亢 妊娠期 甲状腺 甲状腺抗体 hyperthyroidism pregnancy thyroid thyroid antibody
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