摘要
目的针对甲亢病症分别使用抗甲状腺药物与^(131)I这两种治疗方式的治疗效果进行探究。方法从该院2011年12月—2014年12月期间收治的且经过病理诊断均符合甲亢诊断标准的患者中随机抽选80例患者展开调查,对照组患者采取甲状腺药物治疗的方式进行治疗,而实验组患者使用^(131)I进行治疗,对两组患者的治疗效果进行分析和统计。结果对照组患者出现血象降低2例,肝功能受损1例,甲心病5例。而实验组患者出现血象降低1例,未出现肝功能受损和甲心病情况(χ~2=8.476 1,P=0.031 7 <0.05);对照组40例患者发生暂时性甲低3例,永久性甲低4例。而实验组40例患者发生暂时性甲低5例,永久性甲低12例(χ~2=8.648 2,P=0.002 9 <0.05);对照组21例突眼患者,经过治疗之后有12例患者出现突眼减轻或消失的情况,治疗有效率为57.14%,显著低于实验组患者的82.61%(χ~2=8.531 5,P=0.002 6<0.05);对照组患者经过治疗之后出现好转和治愈的患者共34例,治疗有效率为85.00%,显著低于实验组患者的97.50%(χ~2=8.742 6,P=0.032 2<0.05);对照组经过治疗后出现好转和治愈的患者34例,之后有25例患者出现复发情况,复发率为73.53%。而实验组39例出现好转和治愈的患者,之后有2例患者出现复发情况,复发率为5.13%,显著低于对照组患者(χ~2=8.529 0,P=0.002 1<0.05)。结论在临床治疗甲亢的过程中,相较于抗甲状腺药物的治疗,^(131)I的治疗效果更为显著,虽然经过治疗之后仍然存在突眼、甲低等情况,但是治疗之后出现其他系统损伤以及甲亢复发的概率要显著低于使用抗甲状腺药物治疗的患者,值得在临床推广。
Objective To investigate the therapeutic effects of anti-thyroid drugs and 131I treatments for hyperthyroidism.Methods 80 patients were randomly selected from the patients who were admitted to our hospital from December 2011 to December 2014 and whose pathological diagnosis met the diagnostic criteria for hyperthyroidism.The patients in the control group were treated with thyroid medication.The patients in the experimental group were treated with 131I,and the therapeutic effects of the two groups were analyzed and counted.Results In the control group,there were 2 cases of hypoglycemia,1 case of liver function damage,and 5 cases of nail disease.In the experimental group,there was a decrease in hypoglycemia in 1 patient,no liver function damage and nail disease(χ^2=8.476 1,P=0.031 7<0.05);40 patients in the control group had temporary hypothyroidism in 3 cases,permanent hypothyroidism 4 cases.In the experimental group,40 patients had temporary hypothyroidism in 5 cases,permanent hypothyroidism in 12 cases(χ^2=8.648 2,P=0.002 9<0.05);in the control group,21 patients with exophthalmos,after treatment,12 patients had exophthalmos case of alleviation or disappearance,the effective rate was 57.14%,which was significantly lower than 82.61%of the experimental group(χ^2=8.531 5,P=0.002 6<0.05).In the control group,34 patients were improved and cured after treatment.The effective rate of treatment was 85.00%,which was significantly lower than that of the experimental group 97.50%(χ^2=8.742 6,P=0.032 2<0.05).In the control group,34 patients were improved and cured after treatment,and 25 patients subsequently relapsed.The recurrence rate was 73.53%.In the experimental group,39 patients had improved and cured,and 2 patients had recurrence.The recurrence rate was 5.13%,which was significantly lower than that of the control group(χ^2=8.529 0,P=0.002 1<0.05).Conclusion In the course of clinical treatment of hyperthyroidism,the therapeutic effect of 131I is more significant than that of antithyroid drugs.Although there are st
作者
李云浩
靳玉倩
LI Yun-hao;JIN Yu-qian(Department of Internal Medicine,Tangshan Prison Hospital,Tangshan,Hebei Province,063000 China;Department of Endocrinology,Affiliated Hospital of North China University of Technology,Tangshan,Hebei Province,063000 China)
出处
《世界复合医学》
2019年第2期130-132,共3页
World Journal of Complex Medicine
关键词
抗甲状腺药物
131I
甲亢
临床疗效
Antithyroid drugs
131I
Hyperthyroidism
Clinical efficacy
