摘要
目的探究以葡萄糖为显影剂的正电子发射计算机断层显像(^(18)F-FDG PET/CT)对弥漫性结核性腹膜炎(TBP)与腹膜转移瘤(PM)的鉴别诊断价值。方法选取2016年1月1日至2022年12月31日于我院行正电子发射计算机断层显像(PET/CT)检查的腹膜弥漫性病变患者80例作为研究对象,以病理学检查或手术为金标准,将患者分为TBP组(A组20例)、PM组(B组60例),比较两组患者葡萄糖(FDG)代谢分布类型、腹膜增厚类型、病灶直径、大网膜/肠系膜/壁腹膜/腹腔积液最大标准化摄取值(SUVmax)及腹腔积液T/NT,绘制大网膜SUVmax、腹腔积液SUVmax、腹腔积液T/NT的受试者工作特征(ROC)曲线评价诊断TBP与PM的最佳临界值。结果两组患者壁腹膜FDG代谢分布比较无统计学意义(P>0.05)。A组肠系膜、大网膜多为弥漫性FDG代谢分布,而B组多为局限性FDG代谢分布(P<0.05)。比较两组患者腹膜病变形态可知,A组患者壁腹膜均匀增厚、污迹样增厚患者明显多于B组,饼状增厚患者明显少于B组(P<0.05),两组患者结节及肿块样增厚比较,无统计学意义(P>0.05)。A组患者病灶直径多数在3.00cm以下,B组患者病灶直径多数在3.00cm以上,且B组患者病灶平均直径为(3.88±0.79)cm,明显高于A组(2.56±0.53)cm(P<0.05)。两组患者壁腹膜SUVmax比较,无统计学意义(P>0.05),B组患者大网膜、肠系膜SUVmax、腹腔积液SUVmax、腹腔积液T/NT显著高于A组,腹腔积液CT值低于A组(P<0.05)。腹腔积液T/NT曲线下面积最大(0.965),大网膜SUVmax曲线下面积最小(0.808),腹腔积液T/NT、腹腔积液SUVmax、大网膜SUVmax鉴别TBP与PM的最佳临界值分别为0.63、1.79、12.36。结论^(18)F-FDGPET/CT对腹腔积液T/NT的检测鉴别弥漫性TBP与PM的灵敏度最高,具有较高诊断价值。
Objective To investigate the value of positron emission computed tomography(^(18)F-FDG PET/CT)using glucose as a developing agent in the differential diagnosis of diffuse tuberculous peritonitis(TBP)and peritoneal metastases(PM).Methods A total of 80 patients with diffuse peritoneal lesions who underwent positron emission computed tomography(PET/CT)examination in our hospital from January 1,2016 to December 31,2022 were selected as the study objects.Taking pathological examination or surgery as the gold standard,the patients were divided into TBP group(20 cases in group A)and PM group(60 cases in group B).The types of glucose(FDG)metabolic distribution,types of peritoneal thickening,focal diameter,maximum standardized intake value of omental/mesenteric/parietal peritoneal effusion(SUVmax)and peritoneal effusion T/NT were compared between the two groups.Receiver operating characteristic(ROC)curves of omental SUVmax,peritoneal effusion SUVmax and peritoneal effusion T/NT were plotted to evaluate the optimal critical values for diagnosing TBP and PM.Results There was no statistical significance in the distribution of FDG metabolism in parietal peritoneum between 2 groups(P>0.05).The metabolic distribution of FDG in mesentery and omentum in group A was diffuse,while that of FDG in group B was localized(P<0.05).The comparison of peritoneal lesion morphology between the two groups showed that the patients with uniform parietal peritoneal thickening and smudge-like thickening in group A were significantly more than those in group B,and the patients with cake thickening were significantly less than those in group B(P<0.05).There was no statistical significance in nodular and lump-like thickening between the two groups(P>0.05).Most of the lesions in group A were less than 3.00cm in diameter,most of the lesions in group B were more than 3.00cm in diameter,and the average lesion diameter in group B was(3.88±0.79)cm,which was significantly higher than that in group A(2.56±0.53)cm(P<0.05).There was no statistical significan
作者
陈文忠
陈丹丹
楼云龙
宋丽
章明
林炜
Chen Wen-zhong*;Chen Dan-dan;Lou Yun-long;Song Li;ZHANG Ming;LIN Wei(Meizhou People's Hospital,Meizhou 514000,Guangdong Province,China)
出处
《中国CT和MRI杂志》
2024年第12期150-153,共4页
Chinese Journal of CT and MRI
基金
梅州市科技计划项目(2022C0301160)。
关键词
结核性腹膜炎
腹膜转移瘤
正电子发射计算机断层显像
诊断价值
Tuberculous Peritonitis
Peritoneal Metastases
Positron Emission Computed Tomography
Diagnostic Value
