摘要
目的分析大气中二氧化氮(NO_(2))暴露对皮肤病门诊就诊情况的影响,为治理大气污染、保护居民健康提供理论依据。方法2014年1月至2019年12月收集重庆市空气中的NO_(2)日平均浓度、平均相对湿度、平均气温及重庆市某医院皮肤病门诊就诊人次,基于广义相加模型使用时间序列分析方法在不同滞后时间[0~5的单日滞后(lag0~5)和多天的移动平均暴露(lag01~05)]条件下分析NO_(2)浓度与皮肤病门诊就诊量的关系。结果2014年1月至2019年12月重庆市NO_(2)日平均浓度为(40.88±15.06)μg/m^(3),重庆市某医院皮肤病门诊就诊218652人次,日均就诊量为202人次。NO_(2)暴露对该院皮肤病门诊就诊量造成影响,在lag0时的效应值最大,且NO_(2)浓度与皮肤病门诊就诊量呈正相关,即NO_(2)浓度每增加10μg/m^(3)对应的该院皮肤病门诊就诊量变化百分比为0.72%(95%可信区间0.10%~1.34%)。结论暴露于NO_(2)可能会增加机体患皮肤病的风险。
Objective To investigate the effects of NO_(2) exposure on outpatient visits of dermatologic disease,which provides theoretical basis for air pollution control and residents'health protection.Methods The daily mean NO_(2) concentration,relative humidity,daily temperature in Chongqing from January 2014 to December 2019,as well as the dermatologic disease outpatient visits of a hospital in Chongqing during the same period,were collected.Then the time series analysis method with generalized additive model was used to analysis the relationship between NO_(2) concentration and dermatologic disease outpatient visits on the condition of different lag time(lag1-lag5 and lag01-lag05).Results From January 2014 to December 2019,the daily average concentration of NO_(2) in Chongqing was(40.88±15.06)μg/m^(3),and 218652 cases dermatologic disease outpatient visits of the hospital were collected with an average daily dermatologic disease outpatient visits of 202 cases.The results of time series analysis revealed that the effect value reached the maximum on the condition of lag0,and there was a positive correlation between NO_(2) concentration and dermatologic disease outpatient visits on lag0:the corresponding percentage change of dermatologic disease outpatient visits in the hospital increased by 0.72%(95%CI 0.10%-1.34%)for every 10μg/m^(3) increase of NO_(2) concentration.Conclusion The NO_(2) exposure may increase the risk of dermatologic disease outpatient visits for human.
作者
何佩霖
瞿蓉蓉
宋杰
严清娜
熊飞
HE Peilin;QU Rongrong;SONG Jie;YAN Qingna;XIONG Fei(Department of School Health Prevention and Control,Jiulongpo Center for Disease Control and Prevention of Chongqing,Chongqing 400039,China;School of Public Health,Xinxiang Medical University,Xinxiang,Henan 453003,China)
出处
《现代医药卫生》
2024年第22期3810-3814,3820,共6页
Journal of Modern Medicine & Health
基金
重庆市首批公共卫生重点学科(专科)建设项目(YWBF2022072)
重庆市九龙坡区科技计划项目(2019-03-012-Y)。
关键词
二氧化氮
皮肤病
门诊就诊量
广义相加模型
时间序列分析
Nitrogen dioxide
Dermatologic disease
Outpatient visits
Generalized additive model
Time-series analysis
