摘要
目的:探究银杏二萜内酯葡胺注射液联合常规疗法治疗急性脑梗死的临床效果。方法:将2021年7月—2023年7月郓城县中医医院收治的100例急性脑梗死患者随机分成常规组与银杏组,各50例。常规组采取常规疗法治疗,银杏组在常规组基础上采取银杏二萜内酯葡胺注射液治疗。比较两组患者血清学指标、日常生活能力、神经功能、不良反应发生情况。结果:治疗前,两组超敏C反应蛋白(hs-CRP)、血凝素样氧化型低密度脂蛋白受体1(LOX-1)、氧化低密度脂蛋白(Ox-LDL)水平对比,无统计学差异(P>0.05);治疗后,两组hs-CRP、LOX-1、Ox-LDL水平下降,且银杏组低于常规组(P<0.05)。治疗前,两组改良Rankin量表(mRS)、美国国立卫生研究院卒中量表(NIHSS)评分对比,无统计学差异(P>0.05);治疗后,两组mRS、NIHSS评分下降,且银杏组低于常规组(P<0.05)。两组患者不良反应发生率比较,无统计学差异(P>0.05)。结论:银杏二萜内酯葡胺注射液联合常规疗法治疗急性脑梗死的临床效果较好,可改善患者血清指标和神经功能,并提高患者日常生活能力,且不会增加不良反应发生风险。
Objective:To investigate the clinical effect of ginkgo diterpene lactone meglumine injection combined with conventional therapy in treatment of acute cerebral infarction.Methods:A total of 100 patients with acute cerebral infarction treated in Yuncheng Hospital of Traditional Chinese Medicine from July 2021 to July 2023 were randomly divided into conventional group and gingko group,with 50 cases in each group.The conventional group received conventional therapy treatment,and the ginkgo group received ginkgo diterpene lactone meglumine injection treatment on the basis of the conventional group.The serological indexes,daily living ability,neurological function and occurrence of adverse reactions were compared between the two groups.Results:Before treatment,there was no statistical difference in the levels of hypersensitive C-reactive protein(hs-CRP),hemagglutinin-like oxidized low-density lipoprotein receptor 1(LOX-1)and oxidized low-density lipoprotein(Ox-LDL)between the two groups(P>0.05).After treatment,the levels of hs-CRP,LOX-1 and Ox-LDL in the two groups decreased,and the levels in the ginkgo group were lower than those in the conventional group(P<0.05).Before treatment,there was no statistical difference in the scores of modified Rankin Scale(mRS)and National Institutes of Health Stroke Scale(NIHSS)between the two groups(P>0.05).After treatment,the mRS and NIHSS scores in the two groups decreased,and the scores in the ginkgo group were lower than those in the conventional group(P<0.05).There was no statistical difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Ginkgo diterpene lactone meglumine injection combined with conventional therapy has good clinical effects in the treatment of acute cerebral infarction,and can improve the serum indexes and neurological function of patients,enhance the daily living ability of patients,and will not increase the risk of adverse reactions.
作者
刘越
程浩
Liu Yue;Cheng Hao(Endocrinology Department,Yuncheng Hospital of Traditional Chinese Medicine,Heze 274700,Shandong Province,China;Administrative Examination and Approval Guarantee Center of Yuncheng County Administrative Examination and Approval Service Bureau,Heze 274700,Shandong Province,China)
出处
《中国社区医师》
2024年第30期44-46,共3页
Chinese Community Doctors
关键词
急性脑梗死
银杏二萜内酯葡胺注射液
血清学指标
神经功能
不良反应
Acute cerebral infarction
Ginkgo diterpene lactone meglumine injection
Serological index
Neurological function
Adverse reaction
